You are in: eMedicine Specialties > Sports Medicine > Lower Limb Peroneal Tendon SyndromesArticle Last Updated: Feb 10, 2006AUTHOR AND EDITOR INFORMATIONAuthor: Steven Karageanes, DO, Director of Primary Care Sports Medicine Fellowship, Department of Orthopedics, Henry Ford Hospital Center for Athletic Medicine Steven Karageanes is a member of the following medical societies: American Medical Association, American Osteopathic Association, and Michigan State Medical Society Coauthor(s): Kathleen Sharp, MD, Sports Medicine Fellow, Department of Family Practice, Henry Ford Hospital Editors: Gerard A Malanga, MD, Associate Professor, Department of Physical Medicine and Rehabilitation, University of Medicine and Dentistry at New Jersey, New Jersey Medical School; Director of Pain Management, Overlook Hospital; Director of Sports Medicine, Mountainside Hospital; Francisco Talavera, PharmD, PhD, Senior Pharmacy Editor, eMedicine; Russell D White, MD, Professor of Medicine, Department of Community and Family Medicine, University of Missouri-Kansas City School of Medicine, Truman Medical Center Lakewood; Jon Whitehurst, MD, Consulting Staff, Rockford Orthopedic Associates; Wylie D Lowery Jr, MD, Associate Professor, Department of Orthopedic Surgery, George Washington University Author and Editor Disclosure Synonyms and related keywords: tears, subluxation, dislocation, strain, tendonitis, tenosynovitis, peroneal retinaculum tear INTRODUCTIONBackgroundInjuries to the peroneal tendons are common but not always clinically significant. They are misdiagnosed as a lateral ankle sprain most of the time, because isolated injury to the peroneal tendons is rare. Injury can occur in one or both peroneus longus and brevis tendons and is typically classified as acute or chronic. Function can be severely compromised by any tendon disruption; conversely, complete rupture can be asymptomatic. Lesions have been seen in symptomatic patients, as well as in cadaver studies of patients who were presumably asymptomatic. The reason for this variation is not known. Acute injuries of the peroneal tendons include tendinitis, tear/rupture, laceration, and dislocation/subluxation. Acute injuries typically have 1 of 2 mechanisms as the cause: (1) inversion ankle injury, which is often seen with associated anterior talofibular ligament and/or calcaneofibular ligament disruption, and (2) a powerful contraction of the peroneal muscles with a forcefully dorsiflexed foot. Chronic injuries include longitudinal tears and recurrent subluxation of the peroneus brevis tendon. These chronic injuries are usually associated with ankle or subtalar arthritis and ankle instability. FrequencyUnited StatesThe occurrence of injuries to the peroneal tendons is not actually known. DiGiovanni et al found that 25-77% of patients with chronic lateral ankle instability had some type of injury to the peroneal tendons. Fallat et al noted over 33 months that out of 638 acute ankle "sprains" seen at the Oakwood Hospital Downriver Center Emergency Room and Occupational Medicine Clinic, only 83 involved damage to the peroneal tendons, while more than 450 involved the anterior talofibular ligament. Functional AnatomyThe peroneal tendons originate in the lateral compartment of the leg. The peroneus longus originates from the head and proximal two thirds of the fibula, while the brevis originates from the distal two thirds of the fibula. They both have a musculotendinous portion that courses just below the lateral malleolus. At the posterior aspect of the lateral malleolus, they lay within the fibular groove, with the brevis medial and anterior to the longus. The fibular groove forms the anterior border of the fibro-osseous tunnel that the peroneal tendons course through. The inferior retinaculum and the calcaneofibular ligament form the posterior border. The posterior talofibular and the calcaneofibular ligaments form the medial border. The superior retinaculum forms the lateral border. Just inferior to the lateral malleolus, the brevis courses anteriorly crossing over the cuboid to insert on the fifth metatarsal styloid. Inferior to the brevis, the longus turns beneath the cuboid in a tunnel formed by the long plantar ligament and the groove of the cuboid. It then courses to insert onto the first metatarsal and medial cuneiform. In 20% of the population, an os peroneum may be present within the longus tendon as it turns under the cuboid bone. In 0.1% of the population, a structure known as the os vesalianum—a sesamoid bone—is found at the insertion of the peroneus brevis tendon Sport Specific BiomechanicsMost sports have elements of running and lateral movement. Sports such as soccer, basketball, and football can be highly demanding on the lower extremity. The role of the peroneus muscles is to evert the ankle and stabilize its subtalar motion. In balancing the foot, it plays off the posterior tibialis muscle on the opposite side of the tibia. Maximal exertion occurs with side-to-side movement and jumping. The importance of the peroneus muscles is most obvious after lateral ankle sprains. Trauma to the lateral ankle distorts the proprioceptive sense and stretches the connective tissues. The peroneus muscles are often stretched and injured from traction when the foot inverts. Ankle instability ensues and continues until the lateral retinaculum heals, the peroneal muscles recover, and proprioception returns. If the retinaculum does not heal properly and cannot retain its tension to stabilize the peroneal tendons, symptoms of instability may not resolve without further intervention. CLINICALHistoryThe histories for each type of peroneal injury have subtle differences. The key is to have a clinical suspicion and to listen carefully to the patient.
PhysicalThe examination should concentrate on ankle function and stability.
CausesMost peroneal tendon injuries are caused by the typical acute or recurrent lateral ankle sprain. As stated above, isolated injury to the peroneal tendons is rare.
Biomechanical factors can set up the peroneal tendons for injury.
DIFFERENTIALSAchilles Tendonitis Ankle Fracture Ankle Impingement Syndrome Ankle Sprain Athletic Foot Injuries Calcaneofibular Ligament Injury Talofibular Ligament Injury
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| Drug Name | Ibuprofen (Advil, Motrin, Excedrin IB, Ibuprin) |
|---|---|
| Description | DOC for patients with mild to moderate pain. Inhibits inflammatory reactions and pain by decreasing prostaglandin synthesis. |
| Adult Dose | 200-400 mg PO q4-6h while symptoms persist; not to exceed 3.2 g/d |
| Pediatric Dose | 6 months to 12 years: 4-10 mg/kg/dose PO tid/qid >12 years: Administer as in adults |
| Contraindications | Documented hypersensitivity; peptic ulcer disease, recent GI bleeding or perforation, renal insufficiency, or high risk of bleeding |
| Interactions | Coadministration with aspirin increases risk of inducing serious NSAID-related adverse effects; probenecid may increase concentrations and, possibly, toxicity of NSAIDs; may decrease effect of hydralazine, captopril, and beta-blockers; may decrease diuretic effects of furosemide and thiazides; may increase PT when patient is taking anticoagulants (instruct patients to watch for signs of bleeding); may increase risk of methotrexate toxicity; phenytoin levels may be increased when administered concurrently |
| Pregnancy | B - Usually safe but benefits must outweigh the risks. |
| Precautions | Category D in third trimester of pregnancy; caution in congestive heart failure, hypertension, and decreased renal and hepatic function; caution in coagulation abnormalities or during anticoagulant therapy. |
| Drug Name | Naproxen (Anaprox, Naprelan, Naprosyn) |
|---|---|
| Description | For relief of mild to moderate pain; inhibits inflammatory reactions and pain by decreasing activity of cyclo-oxygenase, which results in a decrease of prostaglandin synthesis. |
| Adult Dose | 500 mg PO followed by 250 mg PO q6-8h; not to exceed 1.25 g/d |
| Pediatric Dose | <2 years: Not established >2 years: 2.5 mg/kg/dose PO; not to exceed 10 mg/kg/d |
| Contraindications | Documented hypersensitivity; peptic ulcer disease; recent GI bleeding or perforation; renal insufficiency |
| Interactions | Coadministration with aspirin increases risk of inducing serious NSAID-related adverse effects; probenecid may increase concentrations and, possibly, toxicity of NSAIDs; may decrease effect of hydralazine, captopril, and beta-blockers; may decrease diuretic effects of furosemide and thiazides; may increase PT when patient is taking anticoagulants (instruct patients to watch for signs of bleeding); may increase risk of methotrexate toxicity; phenytoin levels may be increased when administered concurrently |
| Pregnancy | B - Usually safe but benefits must outweigh the risks. |
| Precautions | Category D in third trimester of pregnancy; acute renal insufficiency, interstitial nephritis, hyperkalemia, hyponatremia, and renal papillary necrosis may occur; patients with preexisting renal disease or compromised renal perfusion risk acute renal failure; leukopenia occurs rarely, is transient, and usually returns to normal during therapy; persistent leukopenia, granulocytopenia, or thrombocytopenia warrants further evaluation and may require discontinuation of drug |
Narcotics are used for pain reduction. Pain control is essential to quality patient care. It ensures patient comfort, promotes pulmonary toilet, and enables physical therapy regimens. Many analgesics have sedating properties, which are beneficial for patients that experience pain.
| Drug Name | Acetaminophen (Tylenol, Feverall, Tempra, Aspirin Free Anacin) |
|---|---|
| Description | DOC for pain in patients with documented hypersensitivity to aspirin or NSAIDs, those with upper GI disease, or those taking oral anticoagulants. |
| Adult Dose | 325-650 mg PO q4-6h or 1000 mg tid/qid; not to exceed 4 g/d |
| Pediatric Dose | <12 years: 10-15 mg/kg/dose PO q4-6h prn; not to exceed 2.6 g/d >12 years: 325-650 mg PO q4h; not to exceed 5 doses in 24 h |
| Contraindications | Documented hypersensitivity; known G-6-PD deficiency |
| Interactions | Rifampin can reduce analgesic effects; coadministration with barbiturates, carbamazepine, hydantoins, and isoniazid may increase hepatotoxicity |
| Pregnancy | B - Usually safe but benefits must outweigh the risks. |
| Precautions | Hepatotoxicity possible in chronic alcoholism at various dose levels; severe or recurrent pain or high or continued fever may indicate a serious illness; many OTC products contain acetaminophen, and combined use may result in cumulative doses exceeding recommended maximum dose |
| Drug Name | Acetaminophen and codeine (Tylenol-3) |
|---|---|
| Description | Indicated for the treatment of mild to moderate pain. |
| Adult Dose | 30-60 mg/dose PO based on codeine content q4-6h or 1-2 tab PO q4h; not to exceed 4 g/d of acetaminophen |
| Pediatric Dose | 0.5-1 mg/kg/dose PO based on codeine q4-6h; 10-15 mg/kg/dose based on acetaminophen content; not to exceed 2.6 g/d of acetaminophen |
| Contraindications | Documented hypersensitivity |
| Interactions | Toxicity of codeine increases with CNS depressants, tricyclic antidepressants, MAOIs, neuromuscular blockers, CNS depressants, phenothiazines, and narcotic analgesics; rifampin can reduce analgesic effects of acetaminophen; coadministration with barbiturates, carbamazepine, hydantoins, and isoniazid may increase hepatotoxicity of acetaminophen |
| Pregnancy | C - Safety for use during pregnancy has not been established. |
| Precautions | Caution in patients dependent on opiates because substitution may result in acute opiate-withdrawal symptoms; caution in severe renal or hepatic dysfunction; hepatotoxicity with acetaminophen possible in chronic alcoholism at various dose levels; severe or recurrent pain or high or continued fever may indicate a serious illness; many OTC products contain acetaminophen, and combined use may result in cumulative doses exceeding recommended maximum dose |
| Drug Name | Hydrocodone and acetaminophen (Lorcet-HD, Vicodin, Lortab, Norcet) |
|---|---|
| Description | Drug combination indicated for moderate to severe pain. |
| Adult Dose | 1-2 tab or cap PO q4-6h prn pain |
| Pediatric Dose | <12 years: 10-15 mg/kg/dose acetaminophen PO q4-6h prn; not to exceed 2.6 g/d acetaminophen >12 years: 750 mg acetaminophen PO q4h; not to exceed 10 mg hydrocodone bitartrate per dose or 5 doses/24 h |
| Contraindications | Documented hypersensitivity; high altitude cerebral edema (HACE) or elevated intracranial pressure (ICP) |
| Interactions | Coadministration with phenothiazines may decrease analgesic effects; toxicity increases with CNS depressants or tricyclic antidepressants |
| Pregnancy | C - Safety for use during pregnancy has not been established. |
| Precautions | Tablets contain metabisulfite which may cause hypersensitivity; caution in patients dependent on opiates because substitution may result in acute opiate-withdrawal symptoms; caution in severe renal or hepatic dysfunction |
| Drug Name | Propoxyphene and acetaminophen (Darvocet-N, Darvocet-N 100, Propacet, Wygesic) |
|---|---|
| Description | Drug combination indicated for mild to moderate pain. |
| Adult Dose | 1-2 tab PO q4h prn; not to exceed 600 mg/d |
| Pediatric Dose | Not established |
| Contraindications | Documented hypersensitivity |
| Interactions | May increase serum concentrations of MAOIs, tricyclic antidepressants, carbamazepine, phenobarbital, and warfarin |
| Pregnancy | C - Safety for use during pregnancy has not been established. |
| Precautions | Caution in patients dependent on opiates because substitution may result in acute opiate withdrawal symptoms; caution in severe renal or hepatic dysfunction |
If surgery and/or casting is not required, the patient can usually return to activity in 1-2 weeks with bracing or taping until strength and function are back to 90-100% of the nonaffected ankle.
If surgery is performed, return to play with bracing or taping is usually allowed once the strength and function of the ankle has been rehabilitated to 90% of that in the nonaffected ankle. Once the ankle is close to 100%, the bracing/taping is usually not necessary but permitted.
In most sports injuries, return to play should be allowed when the ankle has a painless range of motion, normal or improved balance, preinjury muscle strength, and no pain with sport-specific functional testing.
Complications of conservative treatment are progression of pain and instability, and possible tendon rupture. Surgical complications vary depending on the procedure. A few common ones include sural nerve injury, progression of symptoms, chronic lateral ankle pain, and loss of range of motion. Any surgery poses a risk of infection and failure of the intent of the procedure.
Several measures can be taken to prevent peroneal tendon injuries: (1) Good pre- and post-exercise stretching of the ankle, (2) gradually increasing the level of activity or training, and (3) fully rehabilitating the ankle after any type of injury. These measures decrease the occurrence of ankle injury and in turn prevent peroneal tendon injury. Other interventions, such as attempting to correct foot abnormalities (eg, pes planus), are also an integral part in prevention.
The prognosis for improvement with conservative treatment is excellent if there is no functional instability requiring surgery. Surgical repairs for acute dislocation and chronic tears are also good. Casting for acute dislocation a success rate of only 50%. Therefore, this option should be reserved for patients with contraindications to surgery.
Educating patients about the importance of ankle rehabilitation after an injury is cornerstone in the prevention of peroneal tendon injuries. Further, stressing the need to stretch before and after exercise is also important.
For excellent patient education resources, visit eMedicine's Foot, Ankle, Knee, and Hip Center and Sprains and Strains Center. Also, see eMedicine's patient education article Ankle Sprain.
| Media file 1: Lateral ankle anatomy demonstrates the peroneal tendons as they course beneath the superior retinaculum. The anterior talofibular, calcaneofibular, and posterior talofibular ligaments are also shown. | |
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| Media file 2: Anterior drawer test, which assesses anterior talofibular ligament stability. The top hand stabilizes while the lower hand translates the calcaneus and talus directly towards the operator. From Karageanes SJ. Principles of Manual Sports Medicine, Lippincott Williams & Wilkins, 2005. | |
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| Media file 3: Tilt test. The operator tilts the talus and calcaneus, not the forefoot. This assesses the integrity of the calcaneofibular ligament. From Karageanes SJ. Principles of Manual Sports Medicine, Lippincott Williams & Wilkins, 2005. | |
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| Media file 4: Dislocated peroneal tendons. Left, Note the course of the tendons anterior to the lateral malleolus. Right, Image demonstrates manual relocation of the displaced tendons. | |
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| Media file 5: Peroneal stability test. The patient pushes the foot laterally against resistance, while the operator monitors the tendon. From Karageanes SJ. Principles of Manual Sports Medicine, Lippincott Williams & Wilkins, 2005. | |
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Peroneal Tendon Syndromes excerpt
Article Last Updated: Feb 10, 2006