Continually Updated Clinical Reference
 
 
  All Sources     eMedicine     Medscape     Drug Reference     MEDLINE
 
eMedicine - Medial Collateral Knee Ligament Injury : Article by

Quick Find
Authors & Editors
Introduction
Clinical
Differentials
Workup
Treatment
Medication
Follow-up
Miscellaneous
References

Related Articles
Femur Injuries and Fractures




Patient Education
Breaks, Fractures, and Dislocations Center

Sports Injury Center

Knee Injury Overview

Knee Injury Causes

Knee Injury Symptoms

Knee Injury Treatment




Author: Thomas M DeBerardino, MD, Director, John A Feagin Jr West Point Sports Medicine Fellowship, Orthopedic Surgery Service, Clinical Instructor in Surgery, Keller Army Community Hospital at West Point

Thomas M DeBerardino is a member of the following medical societies: American Academy of Orthopaedic Surgeons, American Medical Association, American Orthopaedic Association, and American Orthopaedic Society for Sports Medicine

Coauthor(s): Jeffrey C Gundel, MD, Consulting Surgeon, Department of Orthopedic Surgery, North Country Sports Medicine

Editors: Andrew L Sherman, MD, Associate Professor, Departments of Neurological Surgery, Orthopedics, and Rehabilitation, University of Miami Miller School of Medicine; Francisco Talavera, PharmD, PhD, Senior Pharmacy Editor, eMedicine; Russell D White, MD, Professor of Medicine, Department of Community and Family Medicine, University of Missouri-Kansas City School of Medicine, Truman Medical Center Lakewood; Jon Whitehurst, MD, Consulting Staff, Rockford Orthopedic Associates; Wylie D Lowery, Jr, MD, Department of Orthopedic Surgery, Associate Professor, George Washington University

Author and Editor Disclosure

Synonyms and related keywords: MCL injury, tibial collateral knee ligament injury, TCL injury, torn ligament, knee injury

Background

Medial collateral ligament (MCL) injuries of the knee are very common sports-related injuries. The MCL is the most commonly injured knee ligament. Injuries to the MCL occur in almost all sports and in all age groups.

Frequency

United States

The incidence of MCL injuries is impossible to determine because of the wide spectrum of injury severity. Many MCL injuries are minor and may never be evaluated by a physician.

Functional Anatomy

The medial aspect of the knee has been divided into 3 distinct layers based on cadaver dissection. The first layer is the deep fascia, which consists of the sartorius fascia anteriorly and a thin fascial layer posteriorly. The thin posterior fascia covers the popliteal fossa and the heads of the gastrocnemius muscle. The second layer includes the superficial MCL, also known as the tibial collateral ligament. This ligament attaches proximally to the medial femoral epicondyle and to the tibia distally, approximately 4-5 cm distal to the joint line. The parapatellar retinaculum and patellofemoral ligament are within this layer.

The third layer is the knee joint capsule, which attaches proximally and distally at the articular margins. The capsule is divided into thirds from anterior to posterior. The anterior third of the capsule is the thinnest portion. It is attached to the anterior horn of the medial meniscus and is reinforced by the medial retinaculum. The middle third of the capsule consists of the deep medial collateral ligament. It is firmly attached to the mid body of the medial meniscus. Proximal to the meniscal attachment, it is termed the meniscofemoral ligament. Distal to its meniscal attachment, it is termed the meniscotibial ligament. The posterior third of the capsule includes the posterior oblique ligament (POL) and the oblique popliteal ligament. The POL has 3 arms, the superficial, tibial, and capsular.

Sport Specific Biomechanics

The superficial MCL has been shown through serial cutting studies to provide the primary restraint to valgus loads at all degrees of flexion. It is also an important restraint to anterior tibial translation when the anterior cruciate ligament is injured. The superficial MCL acts as a primary restraint to external rotation of the tibia.

Stability of the medial side of the knee is provided by dynamic and static restraints. The static restraints are the superficial MCL and the joint capsule, including the deep MCL and the POL. The semimembranosus muscle, the pes anserine muscles, and the vastus medialis muscle provide dynamic stability. The muscles of the pes include the sartorius, gracilis, and semitendinosus. These muscles flex and internally rotate the tibia. The semimembranosus has 4 attachments: direct, tibial, inferior, and capsular.



History

A thorough history should be obtained prior to performing the physical examination. The following questions should be answered:

  • How and when did the injury occur?
  • What was the mechanism of injury?
  • What was the position of the knee at the time of injury?
  • Was the patient able to ambulate immediately after the injury? If so, is the patient still able to ambulate?
  • Did the knee swell immediately or was swelling delayed?
  • Did the patient experience a sensation of a tearing or hear an audible pop?
  • Did any deformity occur? (Deformity may signify a patella subluxation or dislocation.)
  • Have any prior injuries or fractures occurred?
  • Where is the site of injury within the MCL?

Physical

A complete physical examination of the knee should be performed after a thorough history is obtained. Attention should be directed toward localizing the MCL injury and identifying any associated injuries.

  • Inspection and palpation of the knee should identify the presence and location of point tenderness, localized soft tissue swelling, deformity, or ecchymosis. The region of injury within the ligament should be noted. A large joint effusion indicates an associated intra-articular injury. Outcome can be influenced by the location of the injury within the ligament.


  • The integrity of the MCL is tested with a valgus stress. If any abnormal laxity is noted, the quality of the endpoint should be determined. Testing should be performed in full extension and at 30° of flexion. Grading of the injury is based on the amount of laxity. Any laxity is compared to the opposite knee.


  • Rotation should be compared to the opposite knee when evaluating for associated posteromedial injuries.


  • Anterior and posterior draw signs and a Lachman are performed to rule out associated injuries.


  • Associated injuries include the following:

    • Other structures within the knee may be injured in association with the MCL. The anterior cruciate ligament (ACL) is injured in approximately 20% of grade 1 injuries and as many as 78% of grade 3 injuries.


    • The medial meniscus is injured 5-25% of the time; the incidence increases with severity of the MCL injury.


    • The extensor mechanism, including the vastus medialis obliquus and retinacular fibers, is also injured in 9-21% of the cases.


    • The PCL may be injured, but no incidence has been reported.
       
  • Classification systems include the following:
    • American Medical Association Committee on the Medical Aspects of Sports (1966)

      • Grade 1 - 0-5 mm of opening
      • Grade 2 - 5-10 mm of opening
      • Grade 3 - Greater than 10 mm of opening
         
    • O'Donoghue classification

      • Grade 1 - Few torn fibers, structurally intact
      • Grade 2 - Incomplete tear, no pathologic laxity
      • Grade 3 - Complete tear, pathologic laxity

Causes

Contact, noncontact, and overuse mechanisms are involved in causing MCL injuries.

  • Contact injuries involve a direct valgus load to the knee. This is the usual mechanism in a complete tear.
  • Noncontact, or indirect, injuries are observed with deceleration, cutting, and pivoting motions. These mechanisms tend to cause partial tears.
  • Overuse injuries of the MCL have been described in swimmers. The whip-kick technique of the breaststroke has been implicated. This technique involves repetitive valgus loads across the knee.



Femur Injuries and Fractures

Other Problems to be Considered

Medial meniscal tears
Patella subluxation
Patella dislocation
Tibial plateau fracture
Medial soft tissue contusion
Osteochondral fracture
Osteochondritis desiccans
Tibial plateau fracture
Medial hamstring strain
Pes bursitis
Medial retinacular strain and capsular tears



Imaging Studies

  • Radiography
    • Radiography should be performed to rule out fractures of the tibial plateau, patella, or distal femur. Osteochondral effects can also be observed. Anterior-posterior, lateral, and patellofemoral views are usually sufficient. In skeletally immature patients, stress views may be helpful in identifying an associated physeal injury.

    • The Pellegrini-Stieda lesion is indicative of an old injury and appears as a calcification at the femoral insertion of the MCL.

    • The lateral capsular sign, or Segond fracture, suggests an associated ACL tear. This is a chip of bone still attached to the capsule after the capsule is avulsed from the lateral tibia.

  • MRI: MRI is indicated when associated injuries are suspected. Associated ACL, PCL, and meniscal tears can be identified. Osteochondral fractures and bone bruises may also be identified. Injury of the MCL can be localized to the femoral, midsubstance, or tibial regions.
  • Diagnostic ultrasonography: Recent studies have suggested that diagnostic ultrasonography can be useful in evaluating MCL injuries.

Procedures

  • Joint aspiration: If a significant joint effusion is present, evaluation may be difficult. Using aseptic technique, the knee may be aspirated to allow for a more complete evaluation. A local anesthetic can be injected if the knee is too painful for evaluation.



Acute Phase

Rehabilitation Program

Physical Therapy

The initial treatment of all sprains is similar and follows the RICE protocol with rest, ice, compression, and elevation. Protective weightbearing is instituted with crutches. This is continued until a normal gait is obtained. The severity of the injury dictates further treatment.

Grade 1 and 2 sprains are routinely treated nonoperatively. They may be braced with a knee sleeve or a double-upright hinged knee orthosis, individualized to the patient's discomfort. Crutches are only necessary for a few days. These injuries represent incomplete tears and allow for a rapid return to activities.

Historically, grade 3 tears were treated operatively but currently are routinely treated nonoperatively. In the past, nonoperative treatment meant a long leg cast. Currently, bracing with a hinged knee orthosis is common. Some authors recommend immediate braced increase in range of motion (ROM), while others prefer waiting up to 6 weeks with the knee at 30° of flexion. Crutches are usually necessary for 1-2 weeks.

The goals of therapy are to decrease pain, restore ROM, and regain strength. Crutches are used until weightbearing is comfortable. ROM exercises are performed in a cold whirlpool. Quadriceps strengthening is started with quad sets and progressed to closed-chain exercises as tolerated. Running is allowed when weightbearing is comfortable and is progressed to more narrow S-shaped patterns, until pivoting is comfortable. At this point, sport-specific exercises and drills are added and advanced until the athlete is ready to return to the sport. Return to play is allowed when sport-specific agility testing is performed comfortably. People with grade 1 and 2 injuries usually return to play within 2-3 weeks. People with grade 3 injuries frequently require 6 or more weeks before a return to play.

After sufficient healing of the ligament has occurred, the initial focus of rehabilitation is to restore full ROM. After acceptable knee ROM is restored, the therapist is to concentrate on controlled strengthening. Often in the knee, the functional strength of the quadriceps muscle, especially the medial VMO muscle, is weak and atrophied. After restoration of sufficient strength, the athlete needs to go through sport-specific or function-based training. Upon achieving full strength and pain-free ROM in the lower extremity, the athlete can be cleared to return to their sport, most often without any brace or external support.

Medical Issues/Complications

Persistent instability and laxity may require surgical treatment.

Surgical Intervention

The consensus is that isolated MCL tears rarely require operative repair, while treatment of severe combined ruptures of the MCL and ACL or PCL would require reconstruction. A recent study found that nonoperative and operative treatments of medial collateral ligament injuries lead to equally good results. Another indication for surgical intervention would be persistent instability and consist of tissue repair and imbrication. Often, reinforcement with an allograft is necessary.

Recovery Phase

Rehabilitation Program

Physical Therapy

Long-term outcome studies have shown that almost all patients with grade 1 and 2 injuries have returned to full preinjury activities by 3 months. Isolated grade 3 injuries still allow excellent return to preactivity levels by 6-9 months.



The goals of pharmacotherapy are to reduce morbidity and to prevent complications.

Drug Category: Nonsteroidal anti-inflammatory drugs

Have analgesic, anti-inflammatory, and antipyretic activities. Their mechanism of action is not known, but they may inhibit cyclooxygenase activity and prostaglandin synthesis. Other mechanisms may exist as well, such as inhibition of leukotriene synthesis, lysosomal enzyme release, lipoxygenase activity, neutrophil aggregation, and various cell membrane functions.

Drug NameIbuprofen (Ibuprin, Motrin)
DescriptionDOC for patients with mild to moderate pain. Inhibits inflammatory reactions and pain by decreasing prostaglandin synthesis.
Adult Dose200-400 mg PO q4-6h while symptoms persist; not to exceed 3.2 g/d
Pediatric Dose<6 years: Not established
6 months to 12 years: 4-10 mg/kg/dose PO tid/qid
>12 years: Administer as in adults
ContraindicationsDocumented hypersensitivity; peptic ulcer disease; recent GI bleeding or perforation; renal insufficiency; high risk of bleeding
InteractionsCoadministration with aspirin increases risk of inducing serious NSAID-related adverse effects; probenecid may increase concentrations and, possibly, toxicity of NSAIDs; may decrease effect of hydralazine, captopril, and beta-blockers; may decrease diuretic effects of furosemide and thiazides; may increase PT when taking anticoagulants (instruct patients to watch for signs of bleeding); may increase risk of methotrexate toxicity; phenytoin levels may be increased when administered concurrently
PregnancyB - Usually safe but benefits must outweigh the risks.
PrecautionsCategory D in third trimester of pregnancy; caution in congestive heart failure, hypertension, and decreased renal and hepatic function; caution in coagulation abnormalities or during anticoagulant therapy

Drug NameNaproxen (Anaprox, Naprosyn, Naprelan, Aleve)
DescriptionFor relief of mild to moderate pain; inhibits inflammatory reactions and pain by decreasing activity of cyclooxygenase, which results in a decrease of prostaglandin synthesis.
Adult Dose500 mg PO followed by 250 mg q6-8h; not to exceed 1.25 g/d
Pediatric Dose<2 years: Not established
>2 years: 2.5 mg/kg/dose PO; not to exceed 10 mg/kg/d
ContraindicationsDocumented hypersensitivity; peptic ulcer disease; recent GI bleeding or perforation; renal insufficiency
InteractionsCoadministration with aspirin increases risk of inducing serious NSAID-related adverse effects; probenecid may increase concentrations and, possibly, toxicity of NSAIDs; may decrease effect of hydralazine, captopril, and beta-blockers; may decrease diuretic effects of furosemide and thiazides; may increase PT when taking anticoagulants (instruct patients to watch for signs of bleeding); may increase risk of methotrexate toxicity; phenytoin levels may be increased when administered concurrently
PregnancyB - Usually safe but benefits must outweigh the risks.
PrecautionsCategory D in third trimester of pregnancy; acute renal insufficiency, interstitial nephritis, hyperkalemia, hyponatremia, and renal papillary necrosis may occur; patients with preexisting renal disease or compromised renal perfusion risk acute renal failure; leukopenia occurs rarely, is transient, and usually returns to normal during therapy; persistent leukopenia, granulocytopenia, or thrombocytopenia warrants further evaluation and may require discontinuation of drug

Drug NameKetoprofen (Orudis, Oruvail, Actron)
DescriptionFor relief of mild to moderate pain and inflammation.
Small dosages are initially indicated in small and elderly patients and in those with renal or liver disease.
Doses >75 mg do not increase therapeutic effects. Administer high doses with caution and closely observe patient for response.
Adult Dose25-50 mg PO q6-8h prn; not to exceed 300 mg/d
Pediatric Dose<3 months: Not established
3 months to 12 years: 0.1-1 mg/kg PO q6-8h
>12 years: Administer as in adults
ContraindicationsDocumented hypersensitivity
InteractionsCoadministration with aspirin increases risk of inducing serious NSAID-related adverse effects; probenecid may increase concentrations and, possibly, toxicity of NSAIDs; may decrease effect of hydralazine, captopril, and beta-blockers; may decrease diuretic effects of furosemide and thiazides; may increase PT when taking anticoagulants (instruct patients to watch for signs of bleeding); may increase risk of methotrexate toxicity; phenytoin levels may be increased when administered concurrently
PregnancyB - Usually safe but benefits must outweigh the risks.
PrecautionsCategory D in third trimester of pregnancy; caution in congestive heart failure, hypertension, and decreased renal and hepatic function; caution in coagulation abnormalities or during anticoagulant therapy

Drug NameSulindac (Clinoril)
DescriptionDecreases activity of cyclooxygenase and in turn inhibits prostaglandin synthesis. Results in a decreased formation of inflammatory mediators.
Adult Dose150-200 mg PO bid or 300-400 qd; not to exceed 400 mg/d
Pediatric DoseNot established
ContraindicationsDocumented hypersensitivity; aspirin-, iodide-, or other NSAID-induced hypersensitivity; GI bleeding; renal insufficiency
InteractionsCoadministration with aspirin increases risk of inducing serious NSAID-related adverse effects; probenecid may increase concentrations and, possibly, toxicity of NSAIDs; may decrease effect of hydralazine, captopril, and beta-blockers; may decrease diuretic effects of furosemide and thiazides; may increase PT when taking anticoagulants (instruct patients to watch for signs of bleeding); may increase risk of methotrexate toxicity; phenytoin levels may be increased when administered concurrently
PregnancyC - Safety for use during pregnancy has not been established.
PrecautionsCategory D in third trimester of pregnancy; acute renal insufficiency, hyperkalemia, hyponatremia, interstitial nephritis, and renal papillary necrosis may occur; increases risk of acute renal failure in preexisting renal disease or compromised renal perfusion; low white blood cell counts occur rarely and usually return to reference range in ongoing therapy; discontinuation of therapy may be necessary if persistent leukopenia, granulocytopenia, or thrombocytopenia occurs; caution in anticoagulation defects or in persons who are receiving anticoagulant therapy

Drug Category: Analgesics

Pain control is essential to quality patient care. Analgesics ensure patient comfort, promote pulmonary toilet, and have sedating properties, which are beneficial for patients who have sustained trauma or have sustained injuries.

Drug NamePropoxyphene and acetaminophen (Darvocet N-100)
DescriptionDrug combination indicated for mild to moderate pain.
Adult Dose1-2 tab PO q4h prn; not to exceed 600 mg/d
Pediatric DoseNot established
ContraindicationsDocumented hypersensitivity
InteractionsMay increase serum concentrations of MAOIs, tricyclic antidepressants, carbamazepine, phenobarbital, and warfarin
PregnancyC - Safety for use during pregnancy has not been established.
PrecautionsCaution in patients dependent on opiates, substitution may result in acute opiate withdrawal symptoms; caution in severe renal or hepatic dysfunction

Drug NameAcetaminophen (Tylenol, Feverall, Aspirin-Free Anacin, Tempra)
DescriptionDOC for pain in patients with documented hypersensitivity to aspirin or NSAIDs, with upper GI disease, or who are taking PO anticoagulants.
Adult Dose325-650 mg PO q4-6h or 1000 mg tid/qid; not to exceed 4 g/d
Pediatric Dose<12 years: 10-15 mg/kg/dose PO q4-6h prn; not to exceed 2.6 g/d
>12 years: 325-650 mg PO q4h; not to exceed 5 doses in 24 h
ContraindicationsDocumented hypersensitivity; known G-6-PD deficiency
InteractionsRifampin can reduce analgesic effects of acetaminophen; coadministration with barbiturates, carbamazepine, hydantoins, and isoniazid may increase hepatotoxicity
PregnancyB - Usually safe but benefits must outweigh the risks.
PrecautionsHepatotoxicity possible in people with long-term alcoholism following various dose levels; severe or recurrent pain or high or continued fever may indicate a serious illness; APAP is contained in many OTC products and combined use with these products may result in cumulative APAP doses exceeding recommended maximum dose

Drug NameAcetaminophen and codeine (Tylenol and codeine)
DescriptionIndicated for the treatment of mild to moderate pain.
Adult Dose30-60 mg/dose based on codeine content PO q4-6h or 1-2 tab q4h; not to exceed 4 g/d of acetaminophen
Pediatric Dose0.5-1 mg/kg/dose based on codeine PO q4-6h; 10-15 mg/kg/dose based on acetaminophen content; not to exceed 2.6 g/d of acetaminophen
ContraindicationsDocumented hypersensitivity
InteractionsToxicity of codeine increases with CNS depressants, tricyclic antidepressants, MAOIs, neuromuscular blockers, CNS depressants, phenothiazines, and narcotic analgesics
Rifampin can reduce analgesic effects of acetaminophen; coadministration with barbiturates, carbamazepine, hydantoins, and isoniazid may increase hepatotoxicity of acetaminophen
PregnancyC - Safety for use during pregnancy has not been established.
PrecautionsCaution in patients dependent on opiates because this substitution may result in acute opiate withdrawal symptoms; caution in severe renal or hepatic dysfunction
Hepatotoxicity with acetaminophen possible in people with long-term alcoholism following various dose levels; severe or recurrent pain or high or continued fever may indicate a serious illness; acetaminophen is contained in many OTC products, and combined use with these products may result in cumulative acetaminophen doses that exceed recommended maximum dose

Drug NameHydrocodone and acetaminophen (Vicodin, Lortab, Norcet, Margesic)
DescriptionDrug combination indicated for moderate to severe pain.
Adult Dose1-2 tab or cap PO q4-6h prn
Pediatric Dose<12 years: 10-15 mg/kg/dose acetaminophen PO q4-6h prn; not to exceed 2.6 g/d acetaminophen
>12 years: 750 mg acetaminophen PO q4h; not to exceed 10 mg hydrocodone bitartrate per dose or 5 doses/24 h
ContraindicationsDocumented hypersensitivity; high altitude cerebral edema (HACE); elevated intracranial pressure (ICP)
InteractionsCoadministration with phenothiazines may decrease analgesic effects; toxicity increases with CNS depressants or tricyclic antidepressants
PregnancyC - Safety for use during pregnancy has not been established.
PrecautionsTabs contain metabisulfite, which may cause hypersensitivity; caution in patients dependent on opiates because this substitution may result in acute opiate withdrawal symptoms; caution in severe renal or hepatic dysfunction

Drug NameHydrocodone and ibuprofen (Vicoprofen)
DescriptionDrug combination indicated for short-term (<10 d) relief of moderate to severe acute pain.
Adult Dose1-2 tab PO q4-6h prn pain; not to exceed 5 tab/d
Pediatric DoseNot established
ContraindicationsDocumented hypersensitivity; third trimester of pregnancy
InteractionsCoadministration with aspirin increases risk of inducing serious NSAID-related adverse effects; probenecid may increase concentrations and, possibly, toxicity of NSAIDs; may decrease effect of hydralazine, captopril, and beta-blockers; may decrease diuretic effects of furosemide and thiazides; monitor PT closely (instruct patients to watch for signs of bleeding); may increase risk of methotrexate toxicity; phenytoin levels may be increased when administered concurrently
PregnancyC - Safety for use during pregnancy has not been established.
PrecautionsCaution in impaired renal function, peptic ulcer disease, impaired thyroid function, asthma, hypertension, edema, heart failure, increased intracranial pressure, and erosive gastritis; duration of action may increase in elderly patients

Drug NameOxycodone and acetaminophen (Percocet, Roxilox, Roxicet, Tylox)
DescriptionDrug combination indicated for the relief of moderate to severe pain.
Adult Dose1-2 tab or cap PO q4-6h prn
Pediatric Dose0.05-0.15 mg/kg/dose oxycodone PO q4-6h prn; not to exceed 5 mg/dose of oxycodone
ContraindicationsDocumented hypersensitivity
InteractionsPhenothiazines may decrease analgesic effects of this medication; toxicity increases with coadministration of either CNS depressants or tricyclic antidepressants
PregnancyC - Safety for use during pregnancy has not been established.
PrecautionsDuration of action may increase in elderly patients; be aware of total daily dose of acetaminophen patient is receiving; do not exceed 4,000 mg/24h of acetaminophen; higher doses may cause liver toxicity



Return to Play

Return to play is allowed when sport-specific agility testing is completed comfortably. Usually this requires 90% return of strength compared to the contralateral knee.

Grade 1 and 2 sprains often allow return to play within 1-2 weeks. Grade 3 injuries usually require at least 6 weeks for return to play, although some authors have reported 3-4 weeks.

Complications

Late instability can occur, requiring operative intervention.

Prevention

Prophylactic bracing is controversial, although many athletes wear braces. Some studies recommend bracing after showing a decrease in injury rate. Older studies did not show a decrease in injuries, and some actually demonstrated a slightly increased rate of injuries.

Prognosis

Patients with grade 1 and 2 injuries consistently recover well, and athletes return to play early. Patients with isolated grade 3 injuries also consistently return to full preinjury level, but recovery takes longer.

Education

For excellent patient education resources, visit eMedicine's Breaks, Fractures, and Dislocations Center and Sports Injury Center. Also, see eMedicine's patient education article Knee Injury.



Special Concerns

  • Pediatric patients should be specifically evaluated for an associated physeal injury.



  • Albright JP, Powell JW, Smith W, et al. Medial collateral ligament knee sprains in college football. Effectiveness of preventive braces. Am J Sports Med. Jan-Feb 1994;22(1):12-8. [Medline].
  • Fanelli GC, Edson CJ, Orcutt DR, et al. Treatment of combined anterior cruciate-posterior cruciate ligament-medial-lateral side knee injuries. J Knee Surg. Jul 2005;18(3):240-8. [Medline].
  • Halinen J, Lindahl J, Hirvensalo E, Santavirta S. Operative and Nonoperative Treatments of Medial Collateral Ligament Rupture With Early Anterior Cruciate Ligament Reconstruction: A Prospective Randomized Study. Am J Sports Med. Feb 1 2006;[Medline].
  • Lundberg M, Messner K. Long-term prognosis of isolated partial medial collateral ligament ruptures. A ten-year clinical and radiographic evaluation of a prospectively observed group of patients. Am J Sports Med. Mar-Apr 1996;24(2):160-3. [Medline].
  • Lundberg M, Messner K. Ten-year prognosis of isolated and combined medial collateral ligament ruptures. A matched comparison in 40 patients using clinical and radiographic evaluations. Am J Sports Med. Jan-Feb 1997;25(1):2-6. [Medline].
  • Reider B. Medial collateral ligament injuries in athletes. Sports Med. Feb 1996;21(2):147-56. [Medline].
  • Reider B, Sathy MR, Talkington J, et al. Treatment of isolated medial collateral ligament injuries in athletes with early functional rehabilitation. A five-year follow-up study. Am J Sports Med. Jul-Aug 1994;22(4):470-7. [Medline].
  • Warren LF, Marshall JL. The supporting structures and layers on the medial side of the knee: an anatomical analysis. J Bone Joint Surg Am. Jan 1979;61(1):56-62. [Medline].

Medial Collateral Knee Ligament Injury excerpt

Article Last Updated: May 30, 2006