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Author: Federico C Vinas, MD, Consulting Neurosurgeon, Department of Neurological Surgery, Halifax Medical Center

Federico C Vinas is a member of the following medical societies: American Association of Neurological Surgeons, American College of Surgeons, and American Medical Association

Editors: Andrew D Perron, MD, Residency Director, Department of Emergency Medicine, Maine Medical Center; Francisco Talavera, PharmD, PhD, Senior Pharmacy Editor, eMedicine; Henry T Goitz, MD, Chief, Sports Medicine, Department of Orthopaedic Surgery, Associate Professor, Medical College of Ohio; Jon Whitehurst, MD, Consulting Staff, Rockford Orthopedic Associates; Wylie D Lowery, Jr, MD, Department of Orthopedic Surgery, Associate Professor, George Washington University

Author and Editor Disclosure

Synonyms and related keywords: lumbosacral fractures, sports-related spine fractures, spine fracture, broken back, lumbar spine injury, low back pain, LBP, back injuries, spine injuries, spinal injuries, paraplegia, quadriplegia, acute lumbar spine fracture, lumbar spine fracture, lumbosacral spine fracture, spinal cord injury

Background

Injuries to the lumbar spine have received only a small amount of attention compared with other athletic injuries. This can be explained by a number of reasons. Spinal fractures are relatively uncommon in sport participation compared with other types of injuries; most injuries to the lumbar spine are relatively minor and fit into the category of soft tissue injuries. These soft tissue injuries are usually self-limited and resolve without coming to the attention of health care professionals.

The mechanisms and severity of sport-related lumbar spinal injuries reflect a competitive and risk-taking culture. Lumbar spine bony injuries are often limited to specific sports, most frequently seen in sports such as automobile or motorcycle racing, skydiving, power weight lifting, wrestling, gymnastics, football, horseback riding, and high-speed snow sports. This article reviews the diagnosis and management of acute lumbar vertebral fractures.

Frequency

United States

The epidemiology of thoracic and lumbar spine injuries in athletes is very difficult to document. Most epidemiological studies on lumbar spine injuries in athletes lack prospective data. The thoracolumbar junction and lumbar spine are common sites for fractures due to the high mobility of the lumbar spine compared to the more rigid thoracic spine. Injury to the cord or cauda equina occurs in approximately 10-38% of adult thoracolumbar fractures and in as many as 50-60% of fracture dislocations. The rate of bony injury without neurological consequence is undoubtedly higher.

In the United States, Keene reported an overall rate of 7% for sport-related lumbar injuries in the athlete population. Most of these injuries occurred during practice or preseason conditioning, and only 6% occurred during actual competition. Lumbar spine injuries were significantly more common in football and gymnastics.

Statistics from the US Air Force Academy indicated that 9% of all athletic injuries affect the spinal column. In an analysis of injuries in a professional football team, Ryan et al reported a 6% rate of spinal injuries. Snook reviewed all musculoskeletal injuries sustained by college wrestlers and female gymnasts and found a rate of thoracolumbar spine injuries of 2% and 13%, respectively.

International

Information on the incidence of sports-related spinal injuries in other countries is also limited, and difficult to determine due to differences in data collection and reporting among countries. In England, Williams estimated that spinal injuries account for 15% of all injuries sustained in sports. In this study, injuries to the thoracic and lumbar spine seemed to be more frequent in automobile racing, horseback riding, parachuting, mountain climbing, and weightlifting.

Functional Anatomy

The lumbar spine consists of a mobile segment of 5 vertebrae, located between the relatively immobile segments of the thoracic and sacral segments at either end. The thoracic spine is stabilized by the attached rib cage and intercostal musculature, whereas the sacral segments are fused, providing a stable articulation with the ilium. The lumbar vertebrae are particularly large and heavy compared with the cervical and thoracic vertebrae. The bodies are wider, the pedicles are shorter and heavier, and the transverse processes project somewhat more laterally and ventrally when compared with other spinal segments. The laminae are shorter vertically than the bodies and are bridged by strong ligaments. Finally, the spinal processes are broader and stronger than those in the thoracic and cervical spine.

The lumbar spine must transmit compressive, bending, and twisting forces generated between the upper and lower body. Consequently, as one moves more caudally into the lumbar spine, the muscle groups and ligaments become larger and stronger.

The intervertebral disks consist of 2 components, the annulus fibrosus and the nucleus pulposus. The annulus is a dense fibrous ring located at the periphery of the disk, which has strong attachments to the vertebrae and serves to confine the nucleus pulposus. The lumbar spine is surrounded by powerful musculature and ligaments, which dynamically stabilize the spine.

Sport Specific Biomechanics

The lumbar spine is a complex, 3-dimensional structure that is capable of flexion, extension, lateral bending, and rotation. In the spine, the total range of motion is the result of a summation of the limited movements that occur between the individual vertebrae. Strong muscles and ligaments are crucial for supporting the bony structures and for initiating and controlling movement.

The most common movement of the lumbar spine is flexion. During flexion, anterior compression of the intervertebral disk and widening of the spinal canal occurs along with some sliding movement of the articular process in the zygapophyseal joint. This movement is limited by the posterior ligamentous complex and the dorsal muscles. Extension of the lumbar spine is more limited, producing posterior compression on the disk, narrowing of the spinal canal, and a sliding motion of the zygapophyseal joint. The anterior longitudinal ligament, ventral muscles, lamina, and spinous processes limit the extension of the lumbar spine.

Lateral bending involves lateral compression of the intervertebral disk, along with sliding separation of the zygapophyseal joint on the convex side. An overriding of the zygapophyseal joint occurs on the concave side. The intertransverse ligaments limit the lateral bending of the spine. Rotation of the lumbar spine involves compression of the annulus fibrosus fibers. It is limited by the geometry of the facet joints and the iliolumbar ligaments. The motion of the lumbar spine cannot be considered without evaluating the synchronous movements of the cervical and thoracic spine. The entire spinal column moves as one unit in all planes of motion. Each region of the spine has its own characteristic curvature. These curves allow an upright posture while maintaining the center of gravity over the pelvis and lower limbs. While most rotation is accomplished at the cervical spine, flexion and lateral bending are primarily cervical and lumbar functions.

Spinous process fractures may occur as a result of direct trauma to the posterior spine or as a result of forcible flexion and rotation. These injuries usually are not associated with neurological deficits. Violent muscular contraction or direct trauma can cause fractures of the transverse processes. For example, a football helmet blow to the back can cause fractures of either the spinous or transverse processes. Burst fractures are usually associated with axial loading and compression of the spine. Acute traumatic spondylolisthesis usually is associated with major trauma and extreme hyperextension of the spine.

The intervertebral disks are thick and strong. The annulus fibrosus receives most forces transmitted from one vertebral body to another, and it is designed to resist tension and shearing forces. The nucleus pulposus is designed to resist compression forces. It receives primarily vertical forces from the vertebral bodies and redistributes them in a radial fashion to the horizontal plane. This structure allows the intervertebral disks to dissipate the axial loading.



History

In the assessment of an injured athlete, the history should include a description of the trauma and an exact description of the pain and any exacerbating factors. A past history of any spinal problem should always be obtained. Patients with lumbosacral fractures present with severe pain, deformity, and neurological deficits related to compression of neural structures.

In healthy athletes, a significant traumatic event is required to produce a fracture of the lumbar spine, while in patients with decreased bone density caused by metabolic or endocrine imbalance, a relatively minor trauma can produce a pathological fracture.

Any neurological change at the time of the event, such as weakness, paresthesias, or radicular pain, should be documented. For example, lumbar fractures may cause solitary or multiple radiculopathies. Massive disk herniations, fracture-dislocations, and burst fractures can cause a cauda equina syndrome with variable paraparesis, asymmetrical saddle anesthesia, radiating pain, and sphincter disturbances. Complete damage of the sacral cord and nerve roots is manifested as no motor function or sensation below L1.

  • Classification

    • The most useful classification of lumbar spine fractures is Dennis' 3-column spine stability classification. According to this model, the spine consists of 3 columns.


    • The anterior column is represented by the anterior half of the vertebral body, the anterior half of the annulus fibrosus, and the anterior longitudinal ligament.


    • The middle column consists of the posterior half of the vertebral body, the posterior half of the annulus fibrosus, and the posterior longitudinal ligament.


    • The posterior column is represented by the supraspinous and infraspinous ligaments, ligamentum flavum, articular processes, joint capsules, spinous processes, and the laminae.


    • Instability occurs when 2 or more columns are injured. Because contiguous columns are commonly affected by the same injury, instability is heavily dependent on middle column failure.


    • Most recently, Magerl and colleagues proposed a classification scheme with 3 morphological injury patterns, types A, B, and C, which result from 3 basic forces, compression, distraction, and rotation, respectively. These categories have been applied to all levels of the spine, and subcategories and subdivisions have been described based on the mechanism and severity of the fractures.
       
  • Mechanism of injury and relative force sustained

    • A detailed history must be obtained, if possible, to ascertain the mechanism of injury and the relative force sustained.


    • Individuals who fall often receive hyperflexion or compression injuries, such as spinous process fractures, burst fractures, or traumatic spondylolisthesis. These injuries are commonly associated with pelvic and lower extremity fractures.


    • Automobile racers who were using seat belts during motor vehicle accidents often receive compression or distraction injuries to the spine, which are frequently associated with cervical spine injuries. In these patients, burst fractures and fractures dislocations are relatively common. 


    • Head injuries and extremity fractures commonly accompany vertebral fractures.


    • Abdominal or urological trauma can occur frequently in patients with lumbar fractures.


    • The possible presence of concurrent direct injuries to adjacent intracavitary soft tissue structures, such as renal, spleen, or liver lacerations, must be considered. In general, the more caudal the vertebral injury the greater the biomechanical forces sustained and the greater the propensity for injuries to the pelvis and sacrum.

Physical

The initial management of patients with a lumbar spine injury begins in the field. Any patient who may have a spinal injury is placed on a board in a neutral supine position and immobilized in a neck collar for expeditious transportation to a trauma center. In the emergency department, all patients should be treated as having a spinal injury until this is excluded. Fractures of the thoracolumbar junction can produce a mixture of cord and root syndromes caused by lesions of the conus medullaris and lumbar nerve roots while lower lumbar fractures may cause solitary or multiple root deficits.

The Advanced Trauma Life Support guidelines of the American College of Surgeons should be followed. Stabilization of the patient's airway and hemodynamic status in order to secure adequate oxygenation and tissue perfusion should precede any treatment. A Foley catheter should be inserted. In patients with neurological deficit, immediate peritoneal lavage is often advocated to rule out intra-abdominal injuries. Once the patient has been resuscitated, plain films of the cervical, thoracic, and lumbosacral spine should be taken.

  • Physical examination

    • The physical examination of the athlete with an acute spinal fracture is usually limited by the patient's severe pain.


    • During the spinal examination, the overlying skin should be inspected for abrasions or contusions.


    • Attention should be directed to general deviations from the normal spine curves (ie, thoracic kyphosis, lumbar lordosis).


    • Muscle spasm from pain frequently flattens the spine, whereas spinal fractures may cause a kyphotic or scoliotic deformity.


    • The spine should be palpated for areas of tenderness or fractured, displaced spinous processes.
       
  • Neurologic examination

    • Sometimes, the initial examination of these patients can be difficult because of multiple trauma, spinal shock, or sedation. Any neurologic deficit should be documented according to the American Spinal Injury Association (ASIA) Motor Index.


    • A motor examination should be performed on all conscious patients. Muscle strength and weakness are graded based on a strength scale from 0 to 5, with 5 considered normal and 0 considered paralysis.


    • Muscle strength grading is as follows:

      • Grade 0 - No contraction


      • Grade 1 - Flicker of movement


      • Grace 2 - Can move when gravity is eliminated


      • Grade 3 - Can elevate against gravity


      • Grade 4 - Can move against resistance (-4 for slight resistance, 4 for moderate resistance, and +4 for strong resistance)


      • Grade 5 - Normal strength
         
    • A detailed neurologic evaluation should include detection of a sensory level, posterior column function, and normal and abnormal reflexes and an examination of rectal tone and perianal sensation. The cutaneous abdominal reflex, bulbocavernosus, anal wink, and the presence of a Babinski sign should also be noted and documented. The Beevor sign consists of a cephalic movement of the umbilicus when the patient is asked to elevate the head in the supine position. This is due to paralysis of the lower abdominal muscles.


    • A rectal examination to check for rectal tone and voluntary sphincter function should always be included.


    • Repeated neurologic examinations should be performed and documented at regular intervals to serve as references for improvement or deterioration in the patient's neurologic status over time.


    • In patients with a complete spinal injury (paraplegia or quadriplegia), spinal shock can last 24-48 hours, suppressing all reflex activity below the level of the lesion. The return of reflex activity (bulbocavernosus and anal reflexes) in the absence of any return of sensation or motor function is generally a poor prognostic indicator. Some return of motor or sensory function below the level of the lesion encourages the possibility of some return of useful neurologic function.

Causes

The forces responsible for spinal fractures are compression, flexion, extension, rotation, shear, distraction, or a combination of these mechanisms. In athletes, the most common acute fractures are compression fractures or vertebral endplate fractures caused by sudden axial loading, transverse process avulsion by the origin of the psoas muscle, spinous process avulsions, and acute fracture of the pars interarticularis from hyperextension.

  • Vertebral body compression is more common in athletes with decreased bone density from a cause such as exercise-induced amenorrhea. In adolescents, endplate fractures (Schmorl node) or apophyseal avulsion fractures are relatively common. All these injuries are generally stable and heal with immobilization and nonsurgical management.


  • Spinous process fractures may occur as a result of direct trauma to the posterior spine or as a result of forcible flexion and rotation. These injuries are not usually associated with neurologic deficits. Violent muscular contraction or direct trauma can cause fractures of the transverse processes. For example, a football helmet blow to the back can cause fractures of both spinal and transverse processes. Despite their relatively innocuous appearance, these fractures can cause significant bleeding into the retroperitoneal space, resulting in acute anemia, or ileus.


  • Sports that cause frequent hyperextension of the lumbar spine induce stress on the pars interarticularis. A defect in the pars interarticularis or spondylolysis is common in competitors in sports that require repetitive or prolonged hyperextension of the spine, such as tennis (the serve), volleyball (the spike), and track (the high jump). Athletes with back pain and spondylolysis fall into 2 main groups, (1) those with acute or subacute lesions related to a precipitating episode of hyperextension or trauma and (2) those with well-established, chronic spondylolysis. Although each of the following lesions in isolation can appear benign, the spinal column must be evaluated further to rule out additional injury.

    • Female gymnasts have an incidence of pars defects 4 times greater than the general population. This is presumably the result of gymnastics maneuvers that load the spine in hyperextension (eg, dismounts, back walkovers, aerials).


    • Other athletes at higher risk for pars spondylolysis include ballet dancers, divers, and football linemen.


    • Thoracolumbar fractures have been estimated to occur in 14% of snowmobile injuries, 5% of alpine skiing injuries, and 8% of freestyle skiing injuries.


    • Direct trauma from hockey- or football-related injuries can also cause a fracture of an articular process.
       
  • Acute traumatic spondylolisthesis is usually associated with major trauma and is usually caused by extreme hyperextension. Although patients with a new fracture of the pars interarticularis may have a slip present at the time of the injury, a slip can occur months to years later as the disk degenerates under shear loads that it cannot sustain.



Lumbar Disk Problems in the Athlete
Lumbosacral Disc Injuries
Lumbosacral Discogenic Pain Syndrome
Lumbosacral Facet Syndrome
Lumbosacral Radiculopathy

Other Problems to be Considered

In every patient who has a spinal fracture, the possibility of a preexisting neoplastic or infectious underlying disorder should always be considered. Tumors or osteomyelitis of the lumbar spine may manifest with pathological fractures after a relatively minor trauma. Tumors of the cauda equina or conus, such as ependymomas or neurofibromas, may produce neurologic symptoms that should be recognized.



Lab Studies

  • The evaluation of a patient with an acute lumbar spine fracture should include routine laboratory tests such as a CBC count, electrolyte evaluation, coagulation profile, and blood type and crossmatch. Spinal fractures are often associated with open fractures of the limbs, with significant blood loss and acute anemia.

Imaging Studies

  • The combination of plain radiographs, CT scans, and MRI allows definition of the bony and ligamentous injuries that have been inflicted. The information from these studies helps in the (1) classification of the injury, (2) identification of unstable injuries, and (3) selection of the proper instrumentation to adequately stabilize the unstable bony elements.


  • The initial radiographic examination in the emergency department is a complete spine radiograph series.
    • Analysis of plain radiographs should proceed in an organized sequence beginning with the alignment of both anteroposterior and lateral radiographs; identification of the margins of the vertebral bodies, spinolaminar line, articular facets joints, and interspinous distance; and the position of the transverse processes.


    • Abnormalities of alignment include disruption of the anterior or posterior vertebral body lines, disruption of the spinolaminar line, dislocation of facets, and rotation of spinous processes.


    • Kyphotic angulation is often associated with misalignment and bony fractures. Disruption of the posterior margin of the vertebral body line and widening of the interpediculate distance are important signs of vertebral disruption. Narrowing of a disk space usually accompanies a flexion injury and is seen at the level above the fractured vertebra. Widening of the facet joint or complete baring of the facets indicates a severe posterior ligamentous injury. These findings are usually associated with widening of the interspinous distance.
       
  • Following the analysis of routine spine x-ray films, a CT scan is performed on areas of suspected bony injury.
    • CT scan images best define complex fractures and involvement of the posterior elements of the spine.


    • The scan should include 1 full vertebra above and 1 full vertebra below the level of the fracture, with 3- to 5-mm thickness. Both bone and soft tissue windows should be imaged.


    • Fractures oriented in a horizontal plane, such as Chance fractures and fracture-compression, may not be well visualized with axial scans. Therefore, sagittal and coronal reconstructions should be performed routinely in the evaluation of spinal fractures. Three-dimensional reconstructions can be used to better define the extent of canal compromise and posterior element fractures, although this is not always necessary.
       
  • MRI allows better visualization of the spinal cord and ligamentous structures.
    • On T2-weighted images, high-signal intensity indicates edema. This can be seen in the vertebral body, ligaments, and thoracic spinal cord.


    • Ligament disruptions can sometimes be demonstrated with MRI. The anterior and posterior longitudinal ligaments are best seen on T1- and T2-weighted images, respectively. Frequently, identifying disrupted ligaments is easier than identifying intact ligaments.


    • One disadvantage of MRI in unstable patients is the need for special, non-magnetic mechanical ventilators and other MR-compatible life-support monitors. Some hemodynamically unstable patients may not be candidates for MRI. In addition, patients with multiple traumas frequently have external fixators used to stabilize pelvic fractures, which makes the process of obtaining an MRI difficult.
       
  • When a neurologic deficit is present and a contraindication to MRI is evident, myelography with a postmyelogram CT scan may be used to rule out neural compression. Nonfilling of nerve roots, hematomas, and cauda equina nerve root avulsions may be demonstrated with myelography.

Other Tests

  • Electromyography and nerve conduction studies
    • The examination of muscles with needle electrodes and nerve conduction studies are complementary techniques, usually performed together.

    • Electromyography can show evidence of denervation in the lower extremity muscles or abnormalities in the sphincter muscles.

    • Examination of the paraspinal muscles is also important to distinguish lesions on the spinal cord or cauda equina from lesions in the lumbar or sacral plexus.

    • Nerve conduction studies are an essential part of the evaluation of possible radiculopathy. For example, the demonstration of a superficial peroneal sensory response in the face of L5 symptoms and a sural sensory response in the face of S1 symptoms are useful in localizing the lesions to proximal levels. Results from motor nerve conduction studies are normal in most patients with lumbosacral radiculopathies, and peroneal motor conduction velocity may be mildly slowed.

  • Urodynamic studies: Patients with spinal fractures can develop urinary retention. Methods of objectively testing the behavior of the lower urinary tract during filling, storage, and micturition include uroflowmetry, cystometry, sphincteric electromyography, and combined studies. The appropriate use of urodynamic testing provides valuable information for the evaluation and subsequent treatment of neurourologic dysfunction.
  • Evoked potentials: Somatosensory evoked potentials and nerve action potentials may be used to illustrate preoperative dysfunction and to confirm postoperative improvement.



Acute Phase

Rehabilitation Program

Physical Therapy

Once the spine is stabilized, physical therapy is initiated with the goals of early mobilization, patient and family education (ie, therapeutic exercises, proper body mechanics, precautions), and neuromuscular reeducation.

A physical therapist evaluates range of motion, strength, sensation, bed mobility, balance in sitting and standing, transfers, and ambulation. The goal of physical therapy is to promote independent and safety in ambulation and functional mobility. If a patient reaches the above goals, discharge home with further therapy is recommended. Appropriate equipment is issued once the patient is safe and independent with the necessary equipment such as a cane, walker, or crutches.

Occupational Therapy

Occupational therapy is initiated once the spine is stabilized. The purpose of occupational therapy at this early stage is similar to that of physical therapy.

An occupational therapist evaluates range of motion, strength, sensation, coordination, dexterity, functional muscle use, balance, transfers, and level of independence in activities of daily living. The goal of occupational therapy is to promote maximum independence and safety with activities of daily living, including basic self-care and daily activities such as dressing, bathing, home management, and functional mobility. Further therapy or durable medical equipment such as a bedside commode, assistive devices, and shower chair are recommended if the patient is to be discharged home. Physical and occupational therapy are likely to work in conjunction to promote maximum functional independence.

Medical Issues/Complications

Many potential complications can occur in patients with lumbar fractures. Often, these patients have experienced multiple traumas, and undetected injuries to intracavitary viscera can precipitate a sudden clinical deterioration. Neurologic deterioration can occur from neural traction, compression, or interruption of the vascular supply to the neural elements.

The stress resulting from a traumatic injury, a complicated surgery, and mechanical ventilation can predispose a patient to gastric ulcers. However, the widespread use of prophylaxis measures, such as H2 blockers, sucralfate, and proton pump inhibitors, has reduced the incidence of severe bleeding from stress ulcers.

In patients with spinal cord injury, another frequent source of acute morbidity is sepsis related to urinary tract infections.

Adynamic ileus is common in patients with a complete spinal cord injury. Preventive measures for both conditions include minimizing bed rest, returning to ambulation as early as possible, and limiting the use of narcotics. Early recognition and treatment of these conditions are essential to reduce morbidity and mortality. Initial treatment includes cessation of oral intake, nasogastric suction, insertion of rectal tubes, and cessation of narcotics.

Surgical Intervention

Surgical intervention is often necessary patients with unstable fracture, or neurological deficits related to compression of the neural structures by bonny elements or hematomas, partial cord or cauda equina injuries. The effect of the timing of decompressive surgery on the rate of neurological recovery also has remained unclear. Improved neurological function has been reported with early and late decompression.

A variety of operative techniques are used in the treatment of spinal trauma. The surgical approach used is determined by the level of the injury, characteristics of the fracture, and the location of the neural compression. Modern surgical techniques allow for effective decompression of the neural structures, usually by microsurgical approaches. In patients with unstable fractures, the use of segmental instrumental fixation is often necessary in conjunction with a fusion of the spine, either by an anterior or posterior surgical approach to the spine. This allows for  the reduction and stabilization of the injured segments.

In contrast with patients with spinal cord injuries at the cervical and thoracic spine, patients with nerve root compression at the lumbosacral region often achieve better outcomes following surgical decompression.

Consultations

All patients with compromise of multiple systems or pulmonary or cardiac contusions must be evaluated by a trauma surgeon. The presence of neurologic deficits prompts an evaluation by a neurosurgeon or orthopedic spine surgeon. An orthopedic surgeon is consulted to treat limb fractures. Consultations with other specialists depend on the condition of the patient and the system affected (ie, ophthalmologist; ear, nose, and throat specialist; cardiologist). Treating patients with a multidisciplinary team, including early consultation with a physical therapist, occupational therapist, and rehabilitation specialist, is important.

Recovery Phase

Rehabilitation Program

Physical Therapy

If, upon discharge from the acute care setting, the patient is not safe and independent with activities of daily living, functional mobility, and/or ambulation, an inpatient rehabilitation stay may be necessary. Inpatient rehabilitation is a continuation of comprehensive therapies in a more intense manner. The physical therapist works on bed mobility, transfers, strengthening, and ambulation, if applicable. The goal is to assist the patient in becoming independent with the above skills in a safe manner so that they may return home. Family instruction is provided so family members can assist patients at home with mobility and ambulation upon discharge.

Occupational Therapy

The occupational therapist works on activities of daily living retraining (eg, home safety and management, functional mobility, and basic self-care tasks) and activity tolerance and energy conservation/work simplification techniques. The goal is to assist the patient and family members to achieve the maximum level of independence with activities of daily living and functional mobility. The occupational therapist conducts a home evaluation to assess potential modification needs secondary to environmental barriers, if necessary.

Medical Issues/Complications

Deep Venous Thrombosis (DVT) is a significant potential complication in patients with spinal fractures. Thromboembolism has been reported to occur in as many as 70% of patients with complete motor paralysis. Pulmonary embolism (PE) significantly affects the probability of survival following a spinal fracture.

Infections can occur following spine surgery, especially following a long surgical procedure for a complicated instrumentation placement. Superficial infections should be opened and debrided. The wound may be packed open or closed using retention sutures. Appropriate antibiotics should be employed, starting with coverage against gram-positive coccus and adjusting according to culture results.

Urinary complications continue to be significant sources of morbidity following spinal injuries. In patients with spinal cord injuries, distention of the bladder can lead to autonomic dysreflexia, impairment of bladder sensation, detrusor hyperreflexia, and sphincter dyssynergia, which can lead to renal damage from hydronephrosis or vesicourethral reflux.

Maintenance Phase

Rehabilitation Program

Physical Therapy

Outpatient physical therapy may be necessary for further muscle strengthening and reconditioning of the spinal musculature once the patient is cleared by the physician. A physician's prescription is required for outpatient physical therapy and must include any precautions or contraindications that may still apply. The focus of this phase is an aggressive exercise program for both stretching and strengthening. Pain management modalities may be used to promote decreased pain in order to increase function and participation with therapy. Body mechanics training is also an important focus to reduce the risk of reinjury.

Occupational Therapy

If a spinal injury prevents a patient from returning to their job, a work-hardening program may be warranted. This program is designed to assist an injured person in returning to work. The work-hardening clinician, usually an occupational therapist, designs an individualized treatment plan for each patient. The goals are to build strength, increase endurance, reduce the risk of reinjury, and improve overall function. Work-hardening incorporates physical conditioning, work simulation, and education to achieve the above goals. A doctor's prescription is necessary to begin a work-hardening program.

Medical Issues/Complications

Pseudarthrosis is a cause of chronic pain as result of the malunion of the fusion. It may lead to progressive deformity, neural compromise, and pain. Failure of the instrumentation such as dislodgment or breakage is usually related to a failed fusion.



If the patient arrives at the treating facility within 8 hours of the initial injury and has evidence of a spinal cord injury, 30 mg/kg of methylprednisolone should be given as a slow bolus within the first hour, followed by an infusion of 5.4 mg/kg each hour for the next 23 hours. The use of large doses of steroids can induce stress ulcers and gastritis; therefore, prophylaxis with H2 blockers and/or other antacids should be implemented. This regimen of methylprednisolone is contraindicated in pregnant patients.

Drug Category: Steroids

Steroids, in particular methylprednisolone, have been proven in clinical trials to reduce the formation of free oxygen radicals and improve clinical outcomes following spinal cord injuries.

Drug NameMethylprednisolone (Medrol, Solu-Medrol, Depo-Medrol)
DescriptionSeveral studies have demonstrated that if started within 8 h of injury, this high-dose steroid protocol can improve outcome in patients with a spinal cord injury.
Adult Dose30 mg IV bolus given in the first hour, followed by 5.4 mg/kg/h for 47 h (however, if started within 4 h of the injury, the drip can be given for 23 h)
Pediatric DoseAdminister as in adults
ContraindicationsDocumented hypersensitivity; viral, fungal, or tubercular skin infections
InteractionsCoadministration with digoxin may increase digitalis toxicity secondary to hypokalemia; estrogens may increase levels; phenobarbital, phenytoin, and rifampin may decrease levels (adjust dose); monitor patients for hypokalemia when taking medication concurrently with diuretics
PregnancyC - Safety for use during pregnancy has not been established.
PrecautionsCan cause acute hyperglycemia and ulcers; give concomitant prophylaxis with antacids, H2 blockers, or proton pump inhibitors; hyperglycemia, edema, osteonecrosis, peptic ulcer disease, hypokalemia, osteoporosis, euphoria, psychosis, growth suppression, myopathy, and infections are possible complications of glucocorticoid use

Drug Category: Analgesics

Pain control is essential to quality patient care. Analgesics ensure patient comfort, promote pulmonary toilet, and have sedating properties, which are beneficial for patients who have sustained trauma.

Drug NameMorphine (Duramorph, Astramorph, MS Contin)
DescriptionIn acute phase following acute lumbar bony injury, patients are severely incapacitated by severe pain. Any movement, coughing, or straining produces severe pain. Morphine sulfate is the most-used drug and can be given IV, IM, or IV pump on demand (PCA pump). Some physicians prefer to use codeine because they consider it less sedative.
Adult Dose2-5 mg/h IV/IM up to 30 mg
Pediatric Dose1 mg IV q1h
ContraindicationsDocumented hypersensitivity; hypotension; potentially compromised airway for which establishing rapid airway control would be difficult
InteractionsAnticholinergics may increase risk of severe constipation/paralytic ileus; antidepressants, barbiturates, benzodiazepines, central alpha-2 agonists, MAOIs, sedative, hypnotics, thalidomide, tramadol, and TCAs may increase risk of severe CNS depression; succinylcholines may increase risk of severe bradycardia or cardiac arrest; metoclopramide may increase risk of severe CNS depression or decrease GI prokinetic effects
PregnancyC - Safety for use during pregnancy has not been established.
PrecautionsAll narcotic analgesics produce dose-dependent respiratory and cardiovascular depression; all produce constipation; give concomitant stool softener

Drug Category: Stool softeners

Patients with spinal fractures are at risk of developing constipation and fecal impaction. In these patients, straining causes severe pain. In addition, patients with acute spinal fractures require narcotic analgesics for pain control.

Drug NameDocusate (Colace, Dialose, Surfak)
DescriptionFor patients who should avoid straining during defecation. Allows incorporation of water and fat into stool, causing stool to soften.
Adult Dose50-500 mg PO divided bid/qid (usually 100 mg PO bid)
Pediatric Dose<3 years: 10-40 mg PO divided bid/qid
3-6 years: 20-60 mg PO divided bid/qid
6-12 years: 40-150 mg PO divided bid/qid
ContraindicationsDocumented hypersensitivity; fecal impaction; appendicitis; GI obstruction; mineral oil use
InteractionsDecreases effects of warfarin and increases effects of phenolphthalein
PregnancyC - Safety for use during pregnancy has not been established.
PrecautionsDo not use in patients with fecal impaction, acute appendicitis, acute abdomen, or GI obstruction; prolonged use of medication may result in electrolyte imbalance

Drug Category: H2 Blockers, antihistamine

These agents are reversible competitive blockers of histamine at the H2 receptors, particularly  those in the gastric parietal cells, where they inhibit acid secretion. The H2 antagonists are highly selective, do not affect the H1 receptors, and are not anticholinergic agents.

Drug NameRanitidine
DescriptionInhibits histamine stimulation of the H2 receptor in gastric parietal cells, which in turn reduces gastric acid secretion, gastric volume, and hydrogen ion concentrations.
Adult Dose150 mg PO bid; not to exceed 600 mg/d; alternatively, 50 mg/dose IV/IM q6-8h
Pediatric Dose<12 years: Not established
>12 years: 1.25-2.5 mg/kg/dose PO q12h, not to exceed 300 mg/d; alternatively, 0.75-1.5 mg/kg/dose IV/IM q6-8h, not to exceed 400 mg/d
ContraindicationsDocumented hypersensitivity
InteractionsInhibits CYP-450 3A4 and 2D6; may decrease effects of ketoconazole and itraconazole; may alter serum levels of ferrous sulfate, diazepam, nondepolarizing muscle relaxants, and oxaprozin
PregnancyB - Usually safe but benefits must outweigh the risks
PrecautionsCaution in renal or liver impairment; if changes in renal function occur during therapy, consider adjusting dose or discontinuing treatment; may increase risk of necrotizing enterocolitis in premature infants



Return to Play

Most athletes who experience lumbosacral spine fractures are involved in violent sports or sports that require heavy physical activity or carry a significant risk for recurrence of the injury. Although the decision on when to return to play should be made on a case-by-case basis, many patients with minor spinal injuries, such as an isolated fracture of the transverse or spinous process, may be able to return to play after the injuries have healed (4-8 wk); however, patients who have  vertebral body fractures may require a longer time for the fracture to heal. The time frame depends specifically on the characteristics of the fracture and the specific sport. In some cases, patients who require a major surgical intervention with a spinal fusion and  instrumental fixation may not able to return to participate in that specific sport.

Prognosis

The prognosis of a patient who sustained a sport-related acute fracture of the lumbar spine depends on numerous factors, including the characteristics of the fracture, severity of the associated neurological deficits, associated injuries, and patient's compliance after the discharge. For example, patients who routinely smoke cigarettes have delayed bone healing and a higher risk of developing a pseudoarthrosis. Other patients may injure themselves in their eagerness to return promptly to physical activity or contact sports.

Education

For excellent patient education resources, visit eMedicine's Sports Injury Center and Back, Ribs, Neck, and Head Center. Also, see eMedicine's patient education articles Vertebral Compression Fracture and Back Pain.



Medical/Legal Pitfalls

  • A thoughtful assessment of the implications of the severity of the forces experienced during the injury on both the bony and the ligamentous spinal components is essential in guiding the successful management of the injured athlete. Therefore, careful physical and radiological examinations are crucial to the outcome. Untreated, unrecognized fractures can produce spinal instability and neurologic deficits that initially may not be present but can become permanent.
  • Other potential problems may result from athletes returning to strenuous physical activities too soon, before the bony or ligament structures are completely healed. In some situations, professional athletes (eg, wrestlers) who experienced a major fracture should not be allowed to return to their activities, indefinitely.



Media file 1:  Lateral plain radiograph shows an L3 compression fracture.
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Media type:  X-RAY

Media file 2:  A CT scan with sagittal reconstructions allows better visualization of the compression fracture.
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Media type:  CT

Media file 3:  Image from a sagittal T1-weighted MRI study of a professional driver who was in a rollover motor vehicle accident while racing his car. This figure shows a T-10 unstable burst fracture producing severe kyphotic deformity of the spine. The abnormal signal on the vertebral body and the extradural defect represent a subacute hematoma producing spinal cord compression. The patient had severe paraparesis and underwent an emergency operation. He underwent an anterolateral retroperitoneal approach with a corpectomy and vertebral reconstruction.
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Media type:  MRI

Media file 4:  Postoperative plain x-ray film of patient in Media File 3 shows a vertebral reconstruction using a titanium cage filled with bone and the arthrodesis with a Z plate.
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Media type:  X-RAY

Media file 5:  Axial CT scan of an athlete who had a hyperextension injury resulting in disruption of the posterior spinal elements. This patient had compromise of the anterior and middle spinal columns, resulting in an unstable fracture.
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Media type:  CT

Media file 6:  CT scan with 3-dimensional reconstruction facilitates the assessment of some complex fractures. In this case, the patient experienced a severe compression fracture.
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Media type:  CT

Media file 7:  Sagittal CT scan reconstruction of an athlete who had a burst fracture.
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Media type:  CT

Media file 8:  CT scan with coronal reconstruction of an athlete who had multiple compression fractures.
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Media type:  CT

Media file 9:  MRI of a young female with a severe unstable fracture of L4. The patient had a partial neurological deficit and required urgent surgical fixation.
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Media type:  MRI

Media file 10:  Postoperative radiograph of a patient status post reduction, fusion, and internal fixation the unstable fracture. Note that the anatomical alignment has been restored.
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Media type:  X-RAY

Media file 11:  Sagittal CT reconstruction of a young female who had a skydiving accident. The parachute deployed, but the patient landed on concrete and sustained a lower extremity fracture and a fracture of L1. She was neurologically intact but required an open reduction with a fusion and instrumental fixation of the fracture.
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Media type:  CT



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