
Bone Marrow Failure
This bone marrow film at 400x magnification demonstrates a complete absence of hemopoietic cells. Mo... |

Cold Agglutinin Disease
Cold agglutinin disease. Blood smear showing spherocytic and agglutinated red blood cells.
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Cold Agglutinin Disease
Peripheral blood smear showing several clumps of RBCs with the largest in the cent... |

Dermatologic Manifestations of Hematologic Disease
Dermatologic manifestations of hematologic disease. Koilonychia.
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Folic Acid Deficiency
The chemical structure of folic acid and amethopterin (methotrexate), a folic acid antagonist, shows... |

Folic Acid Deficiency
The transformation of formiminoglutamic acid to glutamic acid is dependent upon both vitamin B-12 an... |

Folic Acid Deficiency
Both folic acid and vitamin B-12 participate in the synthesis of DNA and RNA.
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Folic Acid Deficiency
Histologically, the megaloblastosis caused by folic acid deficiency cannot be differentiated from th... |

Folic Acid Deficiency
Peripheral smear of blood in a patient with pernicious anemia. Macrocytes are observed and some of... |

Folic Acid Deficiency
Bone marrow aspirate from a patient with untreated pernicious anemia. Megaloblastic maturation of er... |