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INFLAMMATORY BOWEL DISEASE RESOURCE CENTER
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Crohn disease is an idiopathic, chronic, transmural inflammatory process of the bowel that can affect any part of the GI tract from the mouth to the anus. Unpredictable flares and remissions characterize the long-term course of this illness.
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The inflammatory bowel diseases (IBDs) are idiopathic diseases, probably involving an immune reaction of the body to its own intestinal tract. Two major IBDs exist: ulcerative colitis and Crohn disease. As the name suggests, ulcerative colitis is limited to the colon; Crohn disease can involve any segment of the gastrointestinal tract from the mouth to the anus. |
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This article focuses on the oral manifestations of Crohn disease, ulcerative colitis, reflux, hepatitis, chronic liver disease, anemias, Langerhans histiocytosis, Sjögren syndrome, Kawasaki disease, Wegener granulomatosis, sarcoidosis, amyloidosis, drug-induced conditions, AIDS infection (eg, candidiasis, herpes, hairy leukoplakia, Kaposi sarcoma, cytomegalovirus), psoriasis, and acanthosis nigricans. |
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Perianal granulomas present some degree of diagnostic difficulty. A spectrum of diseases can produce granulomas of the perianal region and perineum. Most are infectious or inflammatory. Standard histologic diagnosis often does little to clarify the etiology. |
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Ulcerative colitis is a relatively uncommon, chronic, recurrent inflammatory disease of the colon or rectal mucosa. Often a lifelong illness, the condition has profound emotional and social impact on the affected individual. |
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