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Author: Mark Ventocilla, OD, FAAO, Clinical Professor, Michigan College of Optometry; Editor, American Optometric Association Contact Lens and Cornea Section Newsletter; Chief Executive Officer, Elder Eye Care Group, PLC; President, Lakeshore Professional Eyecare, PC

Mark Ventocilla is a member of the following medical societies: American Academy of Optometry and American Optometric Association

Coauthor(s): Donna Wicker, OD, FAAO, Consulting Staff, Department of Ophthalmology, WK Kellogg Eye Center, University of Michigan

Editors: Vytautas A Pakainis, MD, Chief of Ophthalmology, Dorn Veterans Administration Medical Center, Professor of Ophthalmology, Ophthalmology, University of South Carolina School of Medicine; Francisco Talavera, PharmD, PhD, Senior Pharmacy Editor, eMedicine; Steve Charles, MD, Director of Charles Retina Institute; Clinical Professor, Department of Ophthalmology, University of Tennessee College of Medicine; Lance L Brown, OD, MD, Ophthalmologist, Affiliated With Freeman Hospital and St John's Hospital, Regional Eye Center, Joplin, Missouri; Hampton Roy Sr, MD, Associate Clinical Professor, Department of Ophthalmology, University of Arkansas for Medical Sciences

Author and Editor Disclosure

Synonyms and related keywords: functional vision loss, visual field defects, decreased visual acuity, visually impaired, rehabilitation, low vision aids, optical prosthetic device, Implantable Miniature Telescope, IMT



Low vision is a general term that refers to a permanent functional vision loss that cannot be corrected by medication, surgery, or glasses. Low vision patients may experience a wide array of diseases, field defects, and degrees of vision loss. However, in general, low vision can be defined as a bilateral decrement to visual acuity or visual field resulting from a disruption of the visual system. This decreased acuity or field results in an impaired ability to perform work, leisure, or daily living activities.

A low vision examination should detail the kinds and the quality of visual deficits afflicting patients and how they are adapting to their vision loss. This may include a chief complaint, as well as social, functional, and ocular health history as detailed in the sample examination form (see Media file 1). Low vision acuity and refraction often requires such nonstandard acuity measures as the Feinbloom low vision chart with numerals in the size range of Snellen 700 to 10. Distance acuity often is measured at varying distances (eg, 10 ft, 5 ft). Trial lens refraction is recommended to ensure accurate vertex distance to allow for eccentric eye or head position.

Near acuity is measured at 40 cm (ie, 0.40 m) with the patient's correction in place. The add power needed to read average size print (ie, 1 M, 20/50 Snellen equivalent, Jaeger #5) is calculated by taking the reciprocal of the near acuity. For example, a patient reading 4 M print (20/200 Snellen equivalent) at 40 cm would require a +10 diopter (D) add to read 1 M print (1/0.40 m/4 M).

One option to speed up the add calculation is to use the Lighthouse Near Acuity Test chart (at 40 cm test distance), which includes precalculated adds for each acuity (see Media file 2). To determine the necessary magnification, divide the best-corrected acuity by the desired acuity. For example, the best-corrected acuity is 20/200 and the desired level of acuity is 20/40, so the required magnification is 5 X (200/40).



Readers

In patients with low-to-moderate vision loss, the near acuity often can be improved by increasing the bifocal add alone. However, bifocal powers greater than +5.00 D may impede mobility. Hence, separate glasses with a more moderate add may be necessary. Also, demonstrating the reduced focal distance (closer working distance) of high-add prescriptions helps to educate patients so that they know exactly at what distance the reading material should be held (see Media file 3).

Excess convergence demanded by add powers greater than +4.00 D can be relieved by the use of a base-in prism, 2 more than the diopteric power of the add per eye. For example, +6.00 D glasses would have 8 prism diopters base-in for both eyes. Standard prism half glasses are available in +4, +5, +6, +8, +10, and +12 D powers.

Optimal illumination with the light source directed at an angle of 45° to the page minimizes glare. The advantage of high-add readers is that they leave the hands free and are familiar to patients. The primary disadvantage of these readers is the need to train patients to use a much closer reading distance.

Microscopes

Microscopes typically are used when the needed add power is greater than 12 D. Because of the greatly reduced focal length, microscopes often are prescribed monocularly (see Media file 4). In contrast, near telescopes allow the patient to read at a more natural working distance. Near telescopes, like surgical telescopes, have a narrow field of view, but they can be manufactured to focus at any working distance. However, good motor control is essential to maintain the reading material within the field of view.

Handheld magnifiers

To achieve full magnification, handheld magnifiers should be demonstrated with the patient's distance correction in place. The demonstration should begin by placing the magnifier on the page and, then, slowly raising it until the image is at the maximum magnification.

Although handheld magnifiers provide greater magnification than high-add readers and allow for a greater reading distance than microscopes, they require good motor control to be used effectively. Hence, handheld magnifiers often are suggested for short-term reading tasks, such as checking prices in a store or reading items on a menu.

Stand magnifiers

Stand magnifiers are similar to handheld magnifiers, but they have a base that is used to rest the magnifier on the reading page (see Media file 5). Stand magnifiers require less motor control than handheld magnifiers and allow for a greater working distance than high-add reading glasses. Moreover, illuminated stand magnifiers can provide the patient with direct illumination of the reading material.

Fixed-focus stand magnifiers are designed to be viewed at a distance of 40 cm and require a reading add to bring the image into focus. Patients often may wish to use a greater add power than the standard +2.50 D to reduce the working distance and to gain a wider field of view. They provide the clearest image when the patient sights the object on axis. An off-axis view of the object through the magnifiers often produces a distorted image and results in reduced reading facility.

If the patient desires to write or sew under the magnifier and has only moderately impaired vision, then an illuminated stand magnifier mounted on a flexible arm can be used. One such device is the big eye magnifier with a +3.00 D or +6.00 D lens.

Stand magnifiers are especially useful for patients who have glaucoma or retinitis pigmentosa with restricted visual field. For such patients, the reduced field of view provided by the stand magnifier often results in better scanning skills while reading.

The 2 most common reasons for patients to reject these devices are postural fatigue from having to bend over the magnifier and difficulty with manual manipulation of the magnifier. Although practice makes the device more manageable and an adjustable light source with clipboard can improve the posture, patients may prefer the larger field of view provided by closed-circuit televisions (CCTVs) when reading for an extended period of time.



CCTVs provide a larger field of view than other forms of magnification and greatly improve the reading facility for patients with severely impaired vision (see Media file 6). While many new CCTV systems are available, 3 systems are reviewed below to provide a comparison of the generally available features.

Max by Enhanced Vision Systems is a handheld magnifier used like a computer mouse to scan print, which is enlarged and viewed on a television (TV) monitor.

Advantages include the following:

  • Low cost ($349 for black and white, $449 for color)
  • Portable, handheld, mouselike magnifier connects to a TV or computer monitor
  • Inverse polarity available (white letters on black background)
  • Magnification (X16-28 on 20" TV monitor)

Disadvantages include the following:

  • Requires a TV monitor
  • Requires good motor skills to manipulate the mouse
  • Cannot be used for writing

Other enhanced vision systems include the joint optical reflective display (JORDY) with an integrated camera at eye level.

  • This system is particularly beneficial for patients when they are reading. As the patient looks through the camera, a signal is sent to the screens in the glasses. Adjustments can be made with the attached control unit.
  • Such devices enhance useable peripheral retina capabilities. Other features of the JORDY include a full range of distance to near viewing, a visual field of 44 degrees, autofocus, full color, an object locator, and positive or negative contrast.
  • The JORDY is portable because of the device's battery pack. A stand is also available that allows the JORDY to be used as a CCTV with available X50 magnification.
  • Patients with age-related macular degeneration (ARMD) benefit the most from the JORDY's capabilities. However, patients with diabetes and glaucoma have also found the device to be beneficial.

OVAC Mini-Roller is a mini-camera mounted on a rolling stand and provides X8-35 magnification on a 20-inch TV monitor.

Advantages include the following:

  • Low cost ($495)
  • Portable, rolling stand device connects to TV monitor
  • Inverse polarity available
  • Can be used for writing tasks

Disadvantages include the following:

  • Requires some assembly when it is to be connected to a monitor
  • Requires good motor skills
  • Not available in color

Aladdin by Telesensory is a more traditional CCTV that includes a monitor and an X, Y, Z tray table. The patient reads by placing the material on the table and moving the table in any direction.

Advantages include the following:

  • Provides an X, Y, Z tray table so patients can move their text in any direction
  • Provides enlargement up to 62 times
  • Provides reverse polarity (white letters on a black background)
  • Available with a color monitor

Disadvantages include the following:

  • Relatively more expensive; cost varies from $1,700 for a black-and-white monitor to $2,600 for a color monitor
  • Not easily portable



Most new computer operating systems provide some low vision features that often are found under the programs, accessories, and accessibility features. These features include the following:

  • Magnification (X2-9) of both icons and text
  • Moveable magnifier to enlarge any portion of the screen at one time
  • Enhanced-contrast (white letters on black background)
  • No cost to the patient

Zoom text by AI Squared

  • Used to enlarge text and icons on a computer screen
  • X2-16 magnification
  • Mouse magnifier allows for magnification of just part of the computer screen
  • Enables reading email or echo typing
  • Costs $395-795

VisAbility by AI Squared

  • Scans forms and text, which are magnified X2-32 on the patient's monitor
  • Reading mode reads text to the patient
  • Costs $495



Telescopes are typically in clear focus for objects viewed from a distance of 20 feet or more. The doctor should prefocus the telescope on a distant object. The telescope should be aligned by focusing a penlight beam through the telescope onto the patient's pupil. The lowest possible magnification should be chosen to meet the patient's needs, thereby keeping the field of view at a maximum. The patient should wear the prescribed correction or have it placed within the lens of the telescope.

Improvements in telescopic systems include the ability to adjust for distance, intermediate, and near vision. Furthermore, increased fields of view and decreased weight allow patients to increase their reading duration and rate.

The Mini Pencil, a 5 X 10-inch telescope, allows patients to spot objects at intermediate and longer distances. The small size and weight allows increased use to the patient as well as storage capabilities.

Hand-held telescopes are useful for short-term spotting tasks. They are small and inconspicuous and often are prescribed monocularly.

Clip-on telescopes are usually monocular. They are useful when patients need their hands to be free. Patching the other eye is helpful when learning how to see with a clip-on telescope.

Spectacle-mounted telescopes are made by cutting out a hole in the conventional lenses and inserting a telescope. The telescopes may be mounted in a central position or in a high position (bioptic position). See Media file 7. They are best made with the patient's prescription in the telescope lens. Patients view through the conventional lens most of the time and tip their heads down to look through the telescope only when magnification is needed. In some states, they can be used to pass the acuity portion of the driver’s license test. They are useful for long-term distance tasks, such as watching sporting events or bird watching.

Sunglasses are used to reduce the symptoms of glare and photosensitivity.

Corning SPF series are useful, especially for patients with macular degeneration, ocular albinism, and glaucoma. They are more costly than the other forms of sunlight protection.

Unlike conventional sunglasses, the top and sides of NOIR sunglasses shield the patient from excess light. NOIR sunglasses are available in many hues. NOIR 711 is most helpful with macular degeneration. They cost much less than the Corning SPF series.



Adaptive equipment

Nonoptical aids can enhance greatly the patient's abilities to cope with reduced vision in daily life. Adaptive equipment is offered by a wide variety of distributors, including the following:

  • Large print material, such as the New York Times, and the Reader's Digest (see Media file 8), allow patients with low-to-moderate vision loss to read with greater facility.
  • Dial markers offer tactile cues for patients to set gauges on ovens, washers, dryers, and thermostats.
  • Self-threading needles allow patients to thread a needle without seeing the needle eye.
  • Books on tape (talking books) allow patients to keep current on a plethora of topics and to compensate for the lost pleasure of reading.
  • Talking clocks and watches help patients to keep time verbally.
  • Check signing and writing guides are stencils with openings cut out to allow the patient to write the date, amount, or signature without writing above or below the line.
  • Free telephone information calls are provided by most telephone services to patients who send in certification of visual impairment.
  • Descriptive video service provides narrated descriptions of visual elements (eg, actions, costumes, gestures, scene changes) in program.
  • Financial benefits: Patients who are certified as legally blind may be entitled to an extra exemption on their state income tax form and/or a higher standard deduction on their federal income tax form and may qualify for social security disability insurance or supplemental security income benefits.
  • In some states, handicapped parking permits are provided to visually impaired people with certification of visual impairment from an eye care practitioner.
  • Count-a-dose devices assist patients in obtaining the correct number of medications.

Eccentric viewing training

Patients with macular disease may benefit from learning to view objects with their peripheral vision. Instructions for eccentric viewing training are as follows:

  • The boxed "E" (see Media file 9) is used to determine where the patient needs to look to see the E most clearly. That area is marked on the box with an X. This is the eccentric viewing position.
  • Next, the patient is instructed to practice looking away and, then, back to the X.
  • The patient should move the E left and right, while maintaining fixation on the X. If the E becomes blurred or out of focus, then the patient is instructed to place the E centrally and refixate on the X. The exercise is repeated, while moving the E up and down.
  • Next, the patient has to repeat the exercise with an E that does not have an X or lines to guide the patient to the eccentric viewing position.

Contrast

Improving the contrast between images results in better visual recognition. Pouring milk into a white cup against a white tablecloth is one example of poor contrast. Using a different color tablecloth and/or cup can improve the contrast (see Media file 10).



The Implantable Miniature Telescope (IMT), an optical prosthetic device, provides an innovative method of improving visual acuity in patients with moderate or severe ARMD. See Media files 11-13.

The device is a fixed focus telescope (2.2X or 3.0X) mounted in a carrier with 2 rigid haptics. It consists of a glass cylinder 4.4 mm in length and 3.6 mm in diameter with a polymethylmethacrylate carrier.  This visual prosthetic device enlarges retinal images in the central visual field, enabling patients to improve distance and near visual acuity. However, this also causes a severe reduction in the visual field. The fellow eye is needed to provide peripheral vision. In other words, one eye sees the magnified telescopic view, while the other eye maintains the full field of vision.  Each eye is used monocularly, as it is impossible to fuse the 2 images.
 
Patient selection
    
Patient selection is critical to a successful surgical outcome because of the complexity of the surgery and the postoperative rehabilitation required in adapting to the device.  

The IMT is appropriate for a small subset of patients. Selected patients have untreatable macular disease, have a fellow eye capable of mobility, and have a cataract. Because of the complexities of the surgery, removing an intraocular lens (IOL) from a pseudophakic eye in order to implant the IMT is not a viable option at this point.

Patients must understand the procedure and the expected outcome. To demonstrate the concept of magnified central vision with peripheral vision loss, patients must try on a central telescope mounted in a pair of glasses. Patients need to understand that the 2 eyes will not work together, thereby creating a unique monovision concept. This idea is especially challenging to demonstrate in these patients because of the cataract in the eye that will be implanted.  
    
In addition, patients must also understand the pros and cons of this device; they may gain better visual acuity but lose peripheral vision and binocularity.
 
Surgical procedure

The implantation for the telescope prosthesis is a complex procedure beyond typical cataract surgery.  

The telescope has larger dimensions than an IOL, and the incision needs to be around 12 mm.  A large capsulorrhexis of 7 mm with an intact capsular bag is needed for telescope implantation.  First, the cortical lens material is completely removed to prevent residual cortex from being trapped between the telescope and the posterior capsule. A viscoelastic product, such as Healon, is used in the anterior chamber to prevent damage to the endothelium. Both haptics are placed in the capsule, and the IMT is then rotated to stabilize the device, with the haptics at the 6-o'clock position and the 12 o'clock position. This requires considerable surgical skill because of the size and the stiffness of the IMT.
    
Following surgery, patients require a longer course of anti-inflammatory medications as well as postoperative education/rehabilitation. 

Postoperative refractive errors are corrected by spectacles. Because of the central position of the telescope, a separate pair of distance and reading glasses or a high-mounted bifocal may be used.
 
Outcomes

A 2-year multicenter clinical trial of the IMT has been completed, including follow-up on 206 patients (mean age, 76 y) who were operated on by 32 different surgeons.1, 2 All patients had moderate to profound bilateral central vision loss resulting from bilateral, untreatable macular degeneration. The acuity and the visual field in their fellow eye were adequate enough for mobility, since the operated eye was to maintain only central vision. Patients also had significant cataracts in the eye to be implanted.

After 1 year, 67% of eyes with the implant achieved a 3-line or greater improvement in best-corrected distance visual acuity, and 53% of eyes achieved a 3-line improvement in distance and near visual acuity (10% for fellow eye controls).1, 2 Overall, 90% of patients with the device implanted had a 2-line improvement in distance vision after the Phase I trial.1, 2
    
The National Eye Institute 25-item Visual Function Questionnaire (NEI VFQ-25) was used to evaluate changes in perceived visual function in daily living activities.1, 2 The mean NEI VFQ-25 scores improved 7 points from baseline (p<0.01), indicating an improvement in vision-related quality of life.

The endothelial count is critical, as the IMT protrudes through the pupillary plane by up to 0.5 mm, and telescope implantation is associated with endothelial cell loss. Trial results showed that the endothelial cell count was decreased an average of 25%, mostly occurring in the initial 3 months postoperatively and correlating with postsurgical corneal edema.1, 2 There was no evidence of further endothelial trauma in the later postoperative period.

While aborted surgical cases or operative complications occurred, 192 of 206 patients still participated in at least 1-year follow-up after surgery.
 
Rehabilitation concerns

A careful refraction is critical after implanting the telescope. Autorefractors and retinoscopy are not possible with the IMT. Because patients have a central vision of about 50 degrees, they may not adapt to a bifocal; therefore, a separate pair of distance and reading glasses may be used successfully. Another possibility is a very high bifocal for only the IMT eye so that patients may adjust the position only slightly to view through the bifocal prescription. Other low vision devices, such as magnifiers and high-power reading glasses, may be used in conjunction with the IMT. 
   
A manual is being developed for training techniques to assist patients, as reading and writing take practice following telescope implantation, and a series of training sessions are needed.

Coordinating the monovision aspect (ie, one eye for peripheral vision and the other eye for detailed vision) is also challenging. Patients may seem to understand this concept prior to surgery, but they may later comment that they cannot get their 2 eyes to work together.
     
Coordination of care is critical so that patients have the appropriate glasses and other magnification tools to ensure a successful outcome. This multidisciplinary approach includes rehabilitation efforts both before and after surgery.   
    
Pending US Food and Drug Administration (FDA) approval, this option may soon be available for patients, as the IMT has the potential to improve vision-related quality of life in patients with untreatable end-stage ARMD.



For more information regarding low vision services, the following organizations can be contacted:

  • Local state commission for the blind and visually impaired
  • American Foundation for the Blind, 11 Penn Plaza, Suite 300, New York, NY 10001 (1-800-232-5463)
  • National Association for Visually Handicapped, 22 West 21st Street, New York, NY 10010 (212-889-3141)
  • National Library Service for the Blind and Physically Handicapped, Library of Congress, Washington, DC 20542 (1-800-424-8567)
  • National Center for Vision and Aging, Lighthouse International, 111 East 59th Street, New York, NY 10022 (1-800-334-5497)

To purchase low vision supplies, the following companies can be contacted:

  • Maxiaids (800) 522-6294
  • Lighthouse International (800) 829-0500
  • ILA (800) 537-2118
  • LS & S (800) 468-4789
  • Ann Morris (800) 454-3175
  • American Printing House for the Blind (800) 572-0844
  • Carolyn's Products for Enhanced Living (800) 648-2266



Media file 1:  Sample examination form.
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Media file 2:  Lighthouse near acuity chart.
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Media file 3:  Prism half-eye reading glasses.
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Media file 4:  Microscope aid used monocularly at close working distance.
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Media file 5:  Stand magnifier useful for patients with poor dexterity.
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Media file 6:  Closed-circuit television provides greater reading facility, while maintaining a large field of view.
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Media file 7:  Bioptic telescope allowed for driving in some states.
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Media file 8:  Large print material used for patients with low-to-moderate reading impairment.
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Media file 9:  Eccentric "E" used to retrain fixation away from a central scotoma.
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Media file 10:  Increased contrast helps patients maximize visual recognition.
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Media file 11:  Full eye view.
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Media file 12:  Undilated view of Implantable Miniature Telescope.
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Media file 13:  Dilated view of Implantable Miniature Telescope.
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Low Vision Therapy excerpt

Article Last Updated: Mar 3, 2008