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Author: E Bradley Strong, MD, Assistant Professor, Department of Otolaryngology-Head and Neck Surgery, University of California at Davis

E Bradley Strong is a member of the following medical societies: Alpha Omega Alpha and American Rhinologic Society

Editors: Jack A Coleman, MD, Assistant Clinical Professor, Department of Otolaryngology, Middle Tennessee Medical Center; Francisco Talavera, PharmD, PhD, Senior Pharmacy Editor, eMedicine; Stephen G Batuello, MD, Consulting Staff, Colorado ENT Specialists; Christopher L Slack, MD, Otolaryngology-Facial Plastic Surgery, Private Practice, Associated Coastal ENT; Medical Director, Treasure Coast Sleep Disorders; Arlen D Meyers, MD, MBA, Professor, Department of Otolaryngology-Head and Neck Surgery, University of Colorado School of Medicine

Author and Editor Disclosure

Synonyms and related keywords: nasoorbitoethmoid fractures, nasoorbitoethmoid complex, NOE, nasoethmoid complex fractures, nasoethmoid fractures, NOE injury, facial injury, panfacial fracture, ethmoid complex, cerebrospinal fluid, CSF, medial canthal tendon, MCT, frontal sinus, ethmoid sinuses, anterior cranial fossa, orbits, frontal bone, nasal bones

The nasoorbitoethmoid (NOE) complex is the confluence of the frontal sinus, ethmoid sinuses, anterior cranial fossa, orbits, frontal bone, and nasal bones. The intricate anatomy of this area makes NOE injuries one of the most challenging areas of facial reconstruction. Inadequately repaired NOE fractures often result in secondary deformities that are extremely difficult (or impossible) to correct. Long-term sequelae of NOE fractures include blindness, telecanthus, enophthalmos, midface retrusion, cerebral spinal fluid (CSF) fistula, anosmia, epiphora, sinusitis, and nasal deformity. Accurate diagnosis and prompt surgical treatment of NOE fractures are critical to avoid complications and to obtain an aesthetic surgical result.

Pathophysiology

If the primary buttresses of the NOE complex are violated, comminution of the entire complex may occur. This may result in telecanthus, enophthalmos, diplopia, and apparent midface retrusion. Isolated medial canthal tendon disruption releases the normal tension on the medial canthus, resulting in telecanthus. Disruption of the anterior cranial fossa may result in a CSF fistula, while disruption of the ethmoid complex and nasofrontal recess (NFR) may result in sinusitis.

Clinical

Patients with NOE fractures often have associated facial injuries or panfacial fractures.

  • Signs and symptoms of NOE fractures include the following:

    • Nasal and forehead swelling or lacerations
    • Eye, forehead, and nose pain
    • Forehead paraesthesias
    • Diplopia
    • Telecanthus
    • CSF rhinorrhea

  • Initial evaluation

    • Establish ABCs.

    • Diagnose any associated injuries.

    • After stabilization, perform a thorough head and neck examination to reveal injuries to the brain, spine, orbits, and facial skeleton.

    • A team approach involving the otolaryngologist/plastic surgeon, neurosurgeon, and ophthalmologist is recommended.

    • Ophthalmologic consultation is mandatory.

  • Direct examination of the NOE complex

    • Examine the nasal cavity for the presence of CSF.

    • Query all conscious patients about the presence of watery rhinorrhea or salty postnasal drainage.

    • Test bloody fluid that is suspicious for CSF rhinorrhea (see Lab Studies).

    • Examine facial lacerations under sterile conditions to assess depth of penetration or intracranial violation.

    • To evaluate the integrity of the medial canthal tendon, place the thumb and index finger over the nasal root and carefully apply lateral tension to each lower lid. Normally, a defined endpoint to the maneuver is evident without palpable motion at the medial canthus. A lax medial canthal tendon or medial orbital wall motion is consistent with a NOE complex fracture. A periosteal elevator also can be inserted through the nose to palpate the stability of the medial canthal tendon complex.

    • Measure and document telecanthus and enophthalmos.
    • Assess and document pupil responses and extraocular muscle mobility.
    • Palpate the nasal bones for crepitus and comminution.
    • Evaluate the septum for septal hematoma.
    • Evaluate the degree of nasal or midface retrusion. Preinjury photographs may be helpful.



The NOE complex represents the confluence of the nasal, lacrimal, ethmoid, maxillary, and frontal bones. The paired nasal bones attach to the frontal bone superiorly and to the frontal process of the maxilla laterally. The ethmoid bone is located posterior to the nasal bones (see Image 1). The ethmoid air cells are present at birth and enlarge to adult size by age 12 years. The overall growth and size of the ethmoid complex is highly variable among individuals. The ethmoid labyrinth separates the orbits from the nasal cavity, while the fovea ethmoidalis forms the roof of the ethmoid sinuses laterally.

The cribriform plate is located approximately 1 cm inferior to the fovea ethmoidalis, and it forms the roof of the nasal cavity medially. The primary vertical buttresses of the NOE complex run from the frontal bone through the medial orbital region and into the frontal process of the maxillary bone. The primary horizontal buttresses of the NOE complex are the superior and inferior orbital rims (see Images 2-3).

The medial canthal tendon arises from the anterior and posterior lacrimal crests and the frontal process of the maxilla. The medial canthal tendon surrounds the lacrimal sac and diverges to become the orbicularis oculi muscle, tarsal plate, and suspensory ligaments of the eyelids (see Image 4). Normal intercanthal distance is approximately 30-35 mm. Anatomically, this distance equates to one half of the interpupillary distance, or equal to the width of the alar base (see Image 5).

Fracture classification

The key component of NOE complex reconstruction is the bony central fragment onto which the medial canthal tendon inserts. Markowitz et al (1991) devised a classification system based on the degree of central fragmentinjury (see Image 6). Each fracture type is subclassified as either unilateral or bilateral.

  • Type I fractures represent a single noncomminuted central fragment without medial canthal tendon disruption.

  • Type II fractures involve comminution of the central fragment, but the medial canthal tendon remains firmly attached to a definable segment of bone.

  • Type III fractures are uncommon and result in severe central fragment comminution with disruption of the medial canthal tendon insertion.



Lab Studies

  • Beta2-transferrin is the definitive test for CSF rhinorrhea. Collect 1 mL of the suspected fluid in a red top tube. Beta2-transferrin is a "send out" laboratory at most institutions. Watery rhinorrhea that is positive for beta2-transferrin is diagnostic for a CSF leak. Besides CSF, only the vitreous humor of the eye and the perilymph of the ear have been found to contain beta2-transferrin.
  • Bloody rhinorrhea suspicious for CSF can be placed on filter paper and observed for a halo sign. If CSF is present, it diffuses faster than blood and results in a clear halo around the central stain.
  • Routine chemistry analysis of the rhinorrhea may reveal an elevated glucose content consistent with CSF.

Imaging Studies

  • Plain radiographs have limited usefulness in aiding the diagnosis of NOE fractures.

  • Thin-cut (1.5 mm) axial and coronal (when available) CT scans are the criterion standard for the diagnosis of NOE fractures (see Image 7).
    • Axial images reveal injury to the frontal sinus, lamina papyracea, ethmoid complex, nasal septum, and nasal bones.

    • Coronal images detail injuries to the cribriform plate, nasofrontal recess, orbital roof and floor, and lamina papyracea.

    • Contrast enhancement of the CSF can assist with the diagnosis of CSF fistula.



Surgical therapy

  • General goals of surgical therapy include protection of orbital and intracranial contents, prevention of early and late complications (eg, blindness, epiphora), and restoration of aesthetic facial contour (eg, normal intercanthal distance, orbital volume).

  • The insertion of the medial canthal tendon onto the bony central fragment is the focal point of NOE complex reconstruction. The medial canthal tendon-central fragment complex maintains the normal intercanthal distance and outward appearance of the midface.

  • NOE injuries are the most challenging of all facial fractures, and surgical repair is often complex and arduous. Inadequate surgical exposure, imprecise fracture reduction, or poor medial canthal tendon repair almost certainly yields suboptimal results.

Preoperative details

Inform all patients undergoing NOE complex repair of the following risks:

  • Scarring, particularly in patients with male-pattern baldness

  • Bleeding

  • Infection

  • Forehead paresthesias

  • External deformity (eg, telecanthus, nasal deformity)

  • Enophthalmos, diplopia, blindness

  • Epiphora

  • Anosmia

  • CSF leak, meningitis

  • Sinusitis

  • Death

Intraoperative details

Surgical exposure can be obtained through coronal incision, subciliary incision, sublabial incision, or canthal stab incision.

Coronal incision

The coronal incision exposes the frontal bone, nasal bones, superior orbital rims, orbital roof, and frontomaxillary buttress.

The patient is positioned 180° away from the anesthesia. Facial lacerations should be explored to augment surgical access. Unfortunately, lacerations alone are usually inadequate for exposure, diagnosis, and repair of NOE fractures. The hair is parted in a widows-peak pattern 4-6 cm behind the anterior hairline. The hair can be shaved along the incision site in a 1-2 cm strip, although this is not necessary. The scalp is incised and elevated in a subperiosteal plane. A subgaleal plane is used if a dural repair is anticipated (eg, posterior table frontal sinus fracture, known CSF leak). The pericranial flap then can be used for closure of the CSF leak.

Lateral flap dissection is performed between the temporoparietal fascia (superficial temporal fascia) and the temporalis muscle fascia (deep temporal fascia) (see Image 8). The temporoparietal fascia and frontal branch of the facial nerve are elevated with the flap. The supraorbital and supratrochlear neurovascular pedicles are identified and protected. Exposure over the glabella, nasal bones, superior orbital rims, and orbital roof may require release of the supraorbital and supratrochlear neurovascular pedicles. The pedicles are released by outfracturing the inferior portion of the foramina with a fine osteotome.

After completion of the bony repair, the galea aponeurosis and skin are closed in a layered fashion. The periosteum is resuspended carefully at the orbital rims and over the zygomatic arches to avoid postoperative ptosis. Two Penrose drains and a pressure dressing are applied, and care is taken to assure that the ears are not rolled forward under the pressure dressing.

Subciliary incision

The subciliary incision (see Image 9) exposes the inferior orbital rim, orbital floor, a portion of the medial orbital wall, the frontomaxillary buttress, and the lateral nasal bones.

Corneal shields are placed over the eyes bilaterally. A small amount of local anesthesia is infiltrated into the lower lid just below the lash line. A 4-0 silk retention suture is placed through the gray line of the lower eyelid. Superior tension is applied to stabilize the lower eyelid. A subciliary incision is placed parallel to, and 2 mm below, the lash line. The incision extends from the medial lash margin to the lateral canthus. Westcott scissors are used to form a tunnel beneath the orbicularis oculi muscle but superficial to the orbital septum. One blade of the scissors then is placed in the tunnel, and the preseptal space is opened 2-3 cm below the skin incision. This incision preserves a strip of pretarsal orbicularis oculi muscle to support the lower eyelid and reduce the risk of postoperative ectropion.

A Westcott scissor and a cotton swab are used for sharp and blunt dissection between the orbicularis oculi muscle and the orbital septum. The proper plane is relatively avascular. Minor bleeding can be controlled with bipolar cautery. If the dissection is performed too deeply, the orbital septum is violated and orbital fat is exposed. If the dissection is performed too superficially, the orbicularis oculi muscle is cut, which results in increased bleeding, possible skin perforation, and an increased risk of postoperative ectropion.

Once the orbital rim is exposed, the periosteum is incised with a monopolar needle cautery. Careful subperiosteal dissection is performed to expose the orbital floor, medial orbital wall, and frontomaxillary buttress, as necessary. The medial dissection must remain on the orbital rim to avoid injuring the lacrimal apparatus. After reduction and plating of the NOE complex fractures, the periosteum is closed with 4-0 polyglycolic suture. The skin muscle flap is redraped, and the skin incisions are closed with 6-0 absorbable suture. Patients with lower lid laxity may require a lateral tacking stitch from the pretarsal/preseptal orbicularis oculi muscle to the lateral orbital rim.

Transconjunctival incision

Transconjunctival exposure of the orbit: The transconjunctival incision eliminates an external scar and reduces the risk of postoperative ectropion. Unfortunately, the lacrimal apparatus limits the exposure of the medial orbital wall and nasal nasomaxillary buttress. When using a transconjunctival approach (which the author prefers) the author often makes a 8-mm stab incision in the medial lower lid (in a natural skin crease) to obtain access to the nasomaxillary buttress. The palpebral conjunctiva is first infiltrated with a small amount of local anesthesia. Two 4-0 silk sutures are placed through the gray line to retract the lid inferiorly. A lateral canthotomy is performed using a scalpel. An inferior cantholysis is performed using Westcott scissors and microforceps.

Bleeding is controlled with bipolar cautery. The Westcott scissors are used to elevate a transconjunctival plane deep to the lower lid retractors but superficial to the orbital septum (see Image 9). The scissors are then inserted and the conjunctiva is tented upward. A needlepoint electrocautery is used (on very low power) to cauterize the conjunctiva at the proposed incision site. The scissors are used to incise the area. The exposure is carried medially to a point just lateral to the lower lid punctum. Dissection to the orbital rim is completed with the Westcott scissors and a cotton swab. The correct dissection plane is relatively avascular. Once the orbital rim is reached, the needlepoint cautery is used to expose the rim, and the dissection is carried along the floor and medial orbital wall. Once the repair is complete, the conjunctiva is closed with a running 6-0 fast absorbing gut, the lateral canthotomy is closed with a 5-0 absorbing monofilament suture, and theskin

isclosedwith 6-0 nylon.

Sublabial incision

The sublabial incision provides exposure of the piriform aperture, the face of the maxilla, and the frontomaxillary buttress.

The gingivobuccal sulcus is infiltrated with local anesthetic, and electrocautery is used to incise the mucosa. The incision is placed 1-2 cm above the gingival margin and extends from the midline to the canine fossa, leaving an adequate gingival cuff for closure of the incision. The incision can be extended laterally for greater exposure; however, take care not to enter the buccal fat pad, which obstructs the field of view. The dissection is carried to the face of the maxilla. A periosteal elevator is used to expose the face of the maxilla, piriform aperture, maxillary branch of the trigeminal nerve, inferior orbital rim, and the frontomaxillary buttress. After completion of the bony repair, the incision is closed with running, locking, 3-0 chromic suture.

Canthal stab incision

The canthal stab incision allows identification of a severed medial canthal tendon. Local anesthetic is infiltrated over the medial canthal tendon. A 3- to 4-mm horizontal stab incision is placed approximately 5 mm medial to the medial palpebral fissure, and the fibrous tissue making up the medial canthal tendon is dissected free. After medial canthal tendon repair, the wound is closed with deep 4-0 interrupted polyglycolic sutures, and the skin is closed with 6-0 interrupted nylon sutures.

Other exposures

Transcaruncular exposure of the orbit: The transcaruncular approach allows excellent exposure of the medial orbital wall, but it does not allow exposure of the nasal bones or medial canthal tendon.

Glabellar and open-sky incision: This incision is generally avoided because of unfavorable external scars and postoperative paresthesias.

Fracture repair

Surgical repair of facial fractures should be performed from the periphery (ie, the skull base, which is stable) toward the central facial skeleton. Any maxillary or frontal bone fractures should be reduced and plated to provide an accurate template for NOE fracture repair.

  • Type I fractures (see Image 6)

    • Nondisplaced single fragment injuries do not require surgical repair.

    • Displaced type I fractures usually require coronal, transconjunctival, and sublabial exposures.

    • Two separate microplates (1-1.2 mm) are applied from the frontal bone to the central fragment and from the maxilla to the central fragment.

    • An accurate reduction must be maintained until both plates are placed, or the lateral pull of the medial canthal tendon may result in central fragment lateralization and subsequent telecanthus.

    • Application of a single microplate from the frontal bone, across the entire central fragment, and onto the maxilla should be avoided, if possible. Such placement requires more elevation of the periosteum on the central fragment, which may disrupt the medial canthal tendon. Plates placed in this region also may widen the nasal root.


  • Type II fractures (see Image 6)

    • Comminuted fractures require more extensive surgical exposure, microplate reduction, and transnasal wiring.

    • Sublabial, transconjunctival, and coronal incisions are used routinely.

    • A subperiosteal dissection is used to locate, but not avulse, the medial canthal tendon.

    • Holes are drilled in the central fragment above and below the medial canthal tendon. Nonabsorbable suture or 28-gauge stainless steel wire is passed lateral to medial through the central fragmentand twisted tightly on the medial aspect of the central fragment. Separate holes are drilled through the medial orbital wall posterior and superior to the lacrimal fossa.

    • Holes drilled anterior to the lacrimal fossa result in lateral rotation of the central fragment and telecanthus (see Image 10). Drilling above the frontoethmoid suture line should be avoided to decrease the risk of intracranial entry. The cribriform plate lies inferior to the roof of the fovea ethmoidalis (see Image 1). Exit holes are drilled on the contralateral side.

    • A large spinal needle is passed retrograde through the holes toward the NOE injury. The transnasal wires are passed through the lumen of the needle, and the needle is extracted. The wires are secured to a microscrew or plate on the contralateral superior orbital rim. Microplates are applied to rigidly fixate the central fragment to stable medial orbital bone.


  • Type III fractures (see Image 6)

    • Type III fractures are associated with more severe trauma and may require primary bone grafting.

    • Sublabial, transconjunctival, and coronal incisions routinely are required.

    • A higher risk of lacrimal duct injury occurs with type III fractures. If frank nasolacrimal injury is present, the nasolacrimal apparatus should be cannulated and stented.

    • After adequate surgical exposure is obtained, the medial canthal tendon remnant is identified. A medial canthal incision can be used to identify the medial canthal tendon, if necessary. The author has generally been able to identify the tendon via a coronal incision by placing a 27-gauge wire transcutaneously at the medial canthus and identifying the tip of the needle internally. A 28-gauge wire or nonabsorbable suture is then passed through the stump twice and to secure the medial canthal tendon. The bony central fragment is identified, and 2 holes are drilled for insertion of transnasal wires.

    • If the central fragment cannot be identified or reconstituted with a suitable bone fragment in the surgical field (ethmoid or maxillary bone), an outer table calvarial bone graft can be used. Bone grafts must be of adequate size to fill the medial canthal defect. The wire (previously attached to the medial canthal tendon) is passed through the central fragment and twisted securely. The wire then is passed transnasally and fixated as previously described (see Type II fractures). Microplates are applied to rigidly fixate the central fragment to stable medial orbital bone.

    • Type III injuries that result in significant loss of nasal projection are repaired primarily with a calvarial bone graft. After medial canthal tendon reconstruction is complete, an outer table calvarial bone graft is harvested to reconstruct the nasal dorsum. The graft should be positioned to allow for reconstitution of the premorbid nasofrontal angle and extended as far as necessary to provide adequate tip support. The graft is cantilevered off the frontal bone with a miniplate or with 2 position screws (see Image 11).

    • After surgical repair, external bolsters are required to prevent hematoma formation, widening of the nasion, and pseudotelecanthus. Thermally activated external nasal bolsters, commonly used for nasal fractures, can be wrapped in Xeroform gauze and applied to the lateral nasal sidewall. Transnasal wires are passed through the medial canthal region and back through the nose just inferior to the nasal bones. The wires are twisted to apply pressure and reduce soft tissue edema. The underlying tissue is closely observed to avoid tissue necrosis.

Postoperative details

Postoperative ophthalmologic examination is recommended, as well as gross visual acuity checks every 6 hours for a 24-hour period. The Penrose drains are removed from the scalp at 24 hours, and the pressure dressing is discontinued after 3 days. The lead bolsters and scalp sutures are removed at 10 days postoperatively. The patient should be examined and queried again, looking for any evidence of a CSF leak.

Follow-up

Routine follow-up care is performed postoperatively at 2 weeks, 1 month, 3 months, 6 months, and then as needed if revision procedures are necessary. Long-term follow-up care can be difficult in this patient population.

For excellent patient education resources, visit eMedicine's Breaks, Fractures, and Dislocations Center. Also, see eMedicine's patient education articles Facial Fracture and Broken Nose.



  • Persistent lower lid ectropion is an uncommon complication of the subciliary approach and is best avoided by the following:

    • Precise surgical incisions and dissection between the orbital septum and the orbicularis oculi muscle

    • Maintenance of a pretarsal strip of orbicularis oculi muscle below the skin incision

    • Minimizing the use of electrocautery

    • Precise surgical closure with lateral suspension of the orbicularis oculi muscle when lower lid laxity is present

  • Postoperative telecanthus is a relatively common complication of NOE fracture repair and is best avoided by the following:

    • Obtaining adequate surgical exposure

    • Precise reduction of the medial canthal tendon and the bony central fragment

  • Pseudotelecanthus is defined as widening of the nasion with normal intercanthal distance. Pseudotelecanthus occurs when the medial canthal tendon and central fragment are repaired accurately, but the treatment of nasal fractures and the overlying soft tissue is inadequate. This complication is best avoided by the following:

    • Accurate diagnosis and treatment of nasal fractures

    • Appropriate use of lead bolsters and transnasal wires

  • Enophthalmos results from inadequate repair of the medial orbital wall or orbital floor. This complication is best avoided by the following:

    • Accurate diagnosis of orbital blow-out fractures on the preoperative CT scan

    • Adequate surgical exposure and repair of significant orbital blow-out fractures

  • Midface retrusion may occur but is best avoided by the following:

    • Accurate intraoperative assessment of nasal dorsal height (often difficult because of soft tissue edema) and judicious use of primary bone grafting to the nasal dorsum

    • Accurate reduction of associated mid-facial fractures and adequate fixation of the fracture segments with bone plates and screws



Disruption of the delicate ethmoid complex and comminution of the nasal bones can make the repair of NOE complex fractures extremely difficult. These injuries often test the capabilities of even the most experienced surgeons. To obtain an aesthetic surgical result, the surgeon must meticulously identify, accurately reduce, and rigidly fixate the medial canthal tendon and central fragment. Special attention also must be focused on the overlying soft tissue to avoid hematoma, chronic induration, and pseudotelecanthus.



Aesthetic reconstruction of the nasal root and medial canthal region continues to be a significant surgical challenge. Future advances may address this issue with the use of surgical navigation systems and/or intraoperative imaging, which returns the bony architecture to its premorbid state more accurately.



Media file 1:  A diagram of the nasoorbitoethmoid complex is shown. Note that the cribriform plate descends approximately 1 cm below the level of the ethmoid roof (fovea ethmoidalis).
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Media type:  Graph

Media file 2:  Vertical buttresses of the nasoorbitoethmoid complex are depicted.
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Media type:  Graph

Media file 3:  Horizontal buttresses of the nasoorbitoethmoid complex are depicted.
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Media type:  Image

Media file 4:  Anatomy of the medial canthal tendon is shown. The tendon splits around the lacrimal sac and attaches to the anterior and posterior lacrimal crests, as well as to the frontal process of the maxilla. The canthal tendon diverges to become the pretarsal, preseptal, and orbital orbicularis oculi muscle.
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Media type:  Graph

Media file 5:  Midface dimensions are depicted. A normal intercanthal distance is 30-35 mm, which is approximately half of the interpupillary distance and is equivalent to the width of the nasal base.
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Media type:  Image

Media file 6:  Nasoorbitoethmoid complex fractures are classified according to 3 types. (A) Type I fractures involve a single, noncomminuted, central fragment without medial canthal tendon disruption (left-unilateral, right-bilateral). (B) Type II fractures involve comminution of the central fragment without medial canthal tendon disruption (left-unilateral, right-bilateral). (C) Type III fractures result in severe central fragment comminution with medial canthal tendon disruption (left-unilateral, right-bilateral).
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Media type:  Image

Media file 7:  Axial CT scan demonstrates a comminuted nasoorbitoethmoid complex fracture.
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Media type:  CT

Media file 8:  Illustration depicts the fascial planes of the forehead and temple. The temporal branch of the facial nerve runs within the superficial temporal fascia (temporoparietal fascia).
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Media type:  Photo

Media file 9:  Illustration depicts the subciliary approach to the orbital floor and nasoorbitoethmoid complex.
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Media type:  Image

Media file 10:  (Above) Transnasal wires placed anterior to the lacrimal fossa result in rotation of the central fragment laterally, which results in postoperative telecanthus. (Below) Transnasal wires placed posterior and superior to the lacrimal fossa provide adequate support for the medial canthal tendon, and postoperative telecanthus is avoided.
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Media type:  Image

Media file 11:  Reconstruction of nasal dorsum with cantilevered calvarial bone graft is shown.
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Media type:  Image



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  • Markowitz BL, Manson PN, Sargent L, et al. Management of the medial canthal tendon in nasoethmoid orbital fractures: the importance of the central fragment in classification and treatment. Plast Reconstr Surg. May 1991;87(5):843-53. [Medline].
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Nasoorbitoethmoid Fractures excerpt

Article Last Updated: Apr 30, 2007