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Author: Thomas E Benzoni, DO, Medical Director of Mercy Air Care, Consulting Staff, Department of Emergency Medicine, Mercy Medical Center

Thomas E Benzoni is a member of the following medical societies: American College of Emergency Physicians, American College of Osteopathic Emergency Physicians, American Osteopathic Association, and Iowa Medical Society

Editors: Theodore J Gaeta, DO, MPH, FACEP, Clinical Associate Professor, Department of Emergency Medicine, Joan and Sanford Weill Medical College at Cornell University; Vice Chairman and Program Director of Emergency Medicine Residency Program, Department of Emergency Medicine, New York Methodist Hospital; Academic Chair, Adjunct Professor, Department of Emergency Medicine, St George's University School of Medicine; Francisco Talavera, PharmD, PhD, Senior Pharmacy Editor, eMedicine; Tom Scaletta, MD, President, American Academy of Emergency Medicine; Chairperson, Department of Emergency Medicine, Edward Hospital; Assistant Professor of Emergency Medicine, Rush Medical College/Cook County Hospital; John D Halamka, MD, MS, Associate Professor of Medicine, Harvard Medical School, Beth Israel Deaconess Medical Center; Chief Information Officer, CareGroup Healthcare System and Harvard Medical School; Attending Physician, Division of Emergency Medicine, Beth Israel Deaconess Medical Center; Rick Kulkarni, MD, Medical Director, Assistant Professor of Surgery, Section of Emergency Medicine, Yale-New Haven Hospital

Author and Editor Disclosure

Synonyms and related keywords: unguis incarnatus, mycoses, chemical cautery, ingrown toenail, painful toe, swollen toe, tender toe, diabetes, arterial insufficiency, lymphangitis

Background

Ingrown toenails (unguis incarnatus) are a common toenail problem of uncertain etiology. Various causes include poorly fit (tight) footwear, infection, improperly trimmed toenails, trauma, and heredity. The great toe is the most commonly involved. The lateral side is involved more commonly than the medial side.

Pathophysiology

The underlying cause of this condition is a foreign body reaction. When the nail bed is compressed from the side, the edge of the nail then penetrates the cuticle. The presence of the keratinaceous material of the nail in the flesh of the toe sets up a foreign body reaction.

Frequency

United States

The occurrence of this common disorder is poorly measured, because many instances are not brought to the attention of the medical community.

International

The frequency is unknown.

Mortality/Morbidity

The principle morbid condition of this disorder is pain. However, it can be the initiating pathway for more serious disorders in certain patients at risk, especially those with diabetes or arterial insufficiency.

  • Particular attention must be paid to high-risk patients. Referral to specialty clinics for follow-up (eg, surgeon, podiatrist) is recommended.
  • No direct mortality for this disorder exists.

Age

This disorder is not found in the preambulatory stages. Rare in preteens, it is more common in teenagers, and its occurrence increases throughout life.



History

  • Patients have a painful, swollen, and tender toe.
  • When infection is present, the patient may have local discharge.
  • Important components of the history include a previous history of risk factors for diabetes and arterial insufficiency.

Physical

  • The affected toe has all the classic signs of infection: edema, erythema, and warmth.
  • Lymphangitis is rare.
  • The affected side is readily apparent.
  • Inspection for other contributing causes, particularly mycoses, is important.

Causes

Ingrowth of the toenail is generally thought to be multifactorial.

  • Nail length: Cutting the nail so short that it is not constrained by the distal portion of the cuticles, allowing side slippage and penetration of the lateral nail bed by the nail substance.
  • External pressure: Wearing shoes that are so tight they compress the ridges of the cuticles against the relatively stiff nail material, turning the nail into a cutting surface.



Nailbed Injuries


Lab Studies

  • Lab studies have no use for ingrown toenails and should be directed at underlying disorders.

Imaging Studies

  • Radiography should be considered when it is necessary to rule out osteomyelitis (rare) or in the setting of trauma to rule out toe fractures (common).



Emergency Department Care

Once nails have started to grow in, the basement membranes of the cuticle are open to bacterial invasion and action is needed to forestall progression. These conservative measures should be enacted as soon as possible and may be sufficient to render surgical treatment unnecessary.

  • The edge of the nail must be elevated from the bed. This elevation can be accomplished by simply rolling a cotton wisp from the lateral side of the nail gently under the edge of the nail (in the case of a lateral ingrowth). Forcing the cotton wisp in from the tip is much more painful.
  • If the nail is too ingrown to do this without pain, try soaking the foot in warm water with an antibacterial agent. Soaking may soften the nail enough to allow elevation of the edge without much pain.
  • If soaking fails, perform a digital block (outlined below) before elevating the nail edge. The toe is exquisitely sensitive. The block may hurt more than the procedure if it is not slowly performed with a small (30-gauge) needle and buffered lidocaine.
  • Partial nail removal with cauterization of the nail matrix is curative in 70-90% of cases.
  • Alternatively, part of the nail plate may be removed by laser. However, there is little to no advantage to the use of the laser over chemical cautery.
  • Chemical cautery of the nail matrix can be done by using phenol or 10% sodium hydroxide.
    • Obtain informed consent; consent should be obtained by the physician and not delegated. Make no guarantees of cure or lack of complications; explain the risk of infection, regrowth, and reoccurrence; and discuss the proposed procedure.
    • Prepare and drape the toe by using povidone-iodophor or a skin cleanser of choice, and perform a digital block at the metatarsal head or proximal phalanx. Use buffered lidocaine (without epinephrine), and inject 1 mL at each digital nerve.
    • Using a nail cutter, elevate the ingrown portion of the nail, rolling the nail from the ingrown side toward the midline of the toe. Be sure to expose the germinal end of the nail. (This end has a soft, feathered edge.) The proximal end is under the cuticle and usually is white. Cut about one-fourth to one-third of the nail, perpendicular to the end of the nail. Discard the piece after showing it the patient.
    • Place a cotton-tipped applicator, soaked in super-saturated phenol or 10% sodium hydroxide, into the proximal sulcus created by removal of the germinal portion of the nail. Wait 60 seconds; repeat this step. Rinse the site, especially the sulcus, with rubbing alcohol. Use an alcohol-saturated applicator to ensure removal of all chemical.
    • Apply a light gauze dressing, and instruct the patient to change the gauze the next day and then daily for 3-5 days. The patient should expect a slight discharge as the body cleanses the nail bed. Importantly, this discharge should occur as the site improves in appearance; discharge and increasing signs of inflammation may mean infection or an incomplete removal of the nail fragments.

Consultations

Consultation is encouraged for those patients with risk factors (eg, those with diabetes or compromised circulation), related to either the disease or the procedure.



Medications are needed for only those with complications. Antibiotics are not indicated unless lymphangitic spread is noted. Antifungal agents are needed for onychomycosis. Ibuprofen is used for pain.

Drug Category: Analgesics

Pain control is essential to quality patient care. It ensures patient comfort, promotes pulmonary toilet, and enables physical therapy regimens. Most analgesics have sedating properties, which are beneficial for patients who have painful lesions.

Drug NameIbuprofen (Advil, Motrin, Nuprin, and Genpril)
DescriptionUsually the DOC for the treatment of mild to moderate pain, if no contraindications are present. Inhibits inflammatory reactions and pain by decreasing prostaglandin synthesis.
Adult Dose200-400 mg PO q4-6h while symptoms persist; not to exceed 3.2 g/d
Pediatric Dose<6 months: Not established
6 months to 12 years: 30-70 mg/kg/d PO tid/qid; not to exceed 2.4 g/d
>12 years: Administer as in adults
ContraindicationsDocumented hypersensitivity; peptic ulcer disease, recent GI bleeding or perforation, renal insufficiency, or high risk of bleeding
InteractionsCoadministration with aspirin increases risk of inducing serious NSAID-related adverse effects; probenecid may increase concentrations and, possibly, toxicity of NSAIDs; may decrease effect of hydralazine, captopril, and beta-blockers; may decrease diuretic effects of furosemide and thiazides; monitor PT closely (instruct patients to watch for signs of bleeding); may increase risk of methotrexate toxicity; phenytoin levels may be increased when administered concurrently
PregnancyB - Usually safe but benefits must outweigh the risks.
PrecautionsCategory D in third trimester of pregnancy; caution in congestive heart failure, hypertension, decreased renal and hepatic function, anticoagulation abnormalities, or during anticoagulant therapy

Drug NameAcetaminophen (Tylenol, Aspirin Free Anacin)
DescriptionDOC for pain in patients with documented hypersensitivity to aspirin or NSAIDs, those with upper GI disease, or those taking oral anticoagulants.
Adult Dose325-650 mg PO q4-6h or 1000 mg PO tid/qid; not to exceed 4 g/d
Pediatric Dose<12 years: 10-15 mg/kg/dose PO q4-6h prn; not to exceed 2.6 g/d
>12 years: 325-650 mg PO q4h; not to exceed 5 doses in 24 h
ContraindicationsDocumented hypersensitivity; known G-6-PD deficiency
InteractionsRifampin can reduce analgesic effects; coadministration with barbiturates, carbamazepine, hydantoins, and isoniazid may increase hepatotoxicity
PregnancyB - Usually safe but benefits must outweigh the risks.
PrecautionsHepatotoxicity possible in chronic alcoholism following various dose levels; severe or recurrent pain or high or continued fever may indicate a serious illness; many OTC products contain acetaminophen, and combined use may result in cumulative acetaminophen doses exceeding recommended maximum dose

Drug NameAcetaminophen and Codeine (Tylenol with codeine)
DescriptionDrug combination indicated for the treatment of mild to moderate pain.
Adult Dose30-60 mg/dose based on codeine content PO q4-6h or 1-2 tab PO q4h; not to exceed 12 tabs in 24 h
Pediatric Dose0.5-1 mg/kg/dose based on codeine PO q4-6h; 10-15 mg/kg/dose based on acetaminophen content PO; not to exceed 2.6 g/d of acetaminophen
ContraindicationsDocumented hypersensitivity
InteractionsToxicity increases with CNS depressants or tricyclic antidepressants
PregnancyC - Safety for use during pregnancy has not been established.
PrecautionsCaution in patients dependent on opiates (substitution may result in acute opiate-withdrawal symptoms); caution in severe renal or hepatic dysfunction



Further Outpatient Care

  • Follow-up for uncomplicated cases is needed only to reassure the patient.
  • A lot of drainage (but little bleeding) may occur in the 2-3 days following removal. The toe looks better, the patient has less pain, and the redness decreases.
  • Patients with risk factors require close follow-up, as noted in Consultations.

Deterrence/Prevention

  • If inciting factors are present, counseling about prevention is indicated.
  • Preventive measures include the use of properly fitted footwear and correct trimming of nails.
    • Shoes should have a toe box large enough to fit the toes without pressure and to allow for normal spreading of the toes with walking.
    • Nails should be cut straight across with clean, sharp, preferably bulldog-type nail trimmers. Nails should not be cut shorter at the lateral edges.

Complications

  • Complications are very rare, except in those predisposed because of underlying pathologic conditions.
  • Complications include infection and loss of the nail.

Prognosis

  • Generally, the prognosis is excellent.
  • Recurrence and/or regrowth of the treated side occurs in 10-30% of cases.

Patient Education



Medical/Legal Pitfalls

  • Good communication regarding the risks and purposes of the cauterizing procedure is the best protection.



Media file 1:  Appearance of typical ingrown toenail.
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Media type:  Photo

Media file 2:  Cutting the nail.
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Media type:  Photo

Media file 3:  Cauterizing the matrix.
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Media type:  Photo

Media file 4:  Appearance of toenail at end of the cauterizing procedure.
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Media type:  Photo



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Toenails, Ingrown excerpt

Article Last Updated: May 16, 2006