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Emergency Medicine > TRAUMA AND ORTHOPEDICS
Fracture, Elbow
Article Last Updated: Jul 10, 2008
AUTHOR AND EDITOR INFORMATION
Section 1 of 12
Author: Daniel K Nishijima, MD, Staff Physician, Department of Emergency Medicine, State University of New York Downstate at Brooklyn/Kings County Medical Center
Daniel K Nishijima is a member of the following medical societies: American Academy of Emergency Medicine, American College of Emergency Physicians, and Society for Academic Emergency Medicine
Coauthor(s):
Matthew Goldman, MD, Clinical Assistant Professor, Assistant Medical Director, Department of Emergency Medicine, Kings County Hospital Center; Clinical Assistant Professor, Department of Emergency Medicine, Downstate Medical Center
Editors: Francis Counselman, MD, Program Director, Chair, Professor, Department of Emergency Medicine, Eastern Virginia Medical School; Francisco Talavera, PharmD, PhD, Senior Pharmacy Editor, eMedicine; Tom Scaletta, MD, Past-President, American Academy of Emergency Medicine; Chairperson, Department of Emergency Medicine, Edward Hospital; Assistant Professor of Emergency Medicine, Rush Medical College and Cook County Hospital; John D Halamka, MD, MS, Associate Professor of Medicine, Harvard Medical School, Beth Israel Deaconess Medical Center; Chief Information Officer, CareGroup Healthcare System and Harvard Medical School; Attending Physician, Division of Emergency Medicine, Beth Israel Deaconess Medical Center; Rick Kulkarni, MD, Medical Director, Assistant Professor of Surgery, Section of Emergency Medicine, Yale-New Haven Hospital
Author and Editor Disclosure
Synonyms and related keywords:
broken arm, broken elbow, elbow fracture, radial head fracture, olecranon fracture, supracondylar fracture, intercondylar fracture, epicondyle fracture, medial epicondyle fracture, lateral epicondyle fracture, condyle fracture, medial condyle fracture, lateral condyle fracture, trochlea fracture, capitellum fracture
Background
Elbow fractures are commonly encountered in the acute care setting. Injury patterns for children and adults are quite different. Fractures of the elbow include extra-articular and intra-articular fractures. Extra-articular fractures include intercondylar fractures, supracondylar fractures, epicondylar fractures, and condyle fractures. Intra-articular fractures include trochlea and capitellum fractures, radial head, proximal ulnar fractures.1 The examining physician must perform a thorough neurovascular examination with all suspected elbow fractures; recognize subtle fracture patterns; provide adequate immobilization; and assess whether fractures require admission, immediate orthopedic evaluation, or less urgent referral.
Anatomy
The elbow is a hinge joint composed of 3 bones: the ulna, the radius, and the humerus. The 3 main articulations of the elbow are (1) the humeroradial articulation, which is formed by the radial head and the capitellum of the humerus; (2) the humeroulnar articulation, which is formed by the ulnar notch and the trochlea of the humerus; and (3) the superior radioulnar articulation, which is formed by the proximal part of the ulna and the radius. All articulations are contained in one synovial-lined capsule, which typically encases a hemarthrosis following injury. Two main movements occur at the elbow: flexion and extension, which occurs primarily at the humeroulnar articulation, and pronation and supination, which occurs primarily at the radioulnar articulation.
Pathophysiology
Fracture patterns vary widely due to the mechanism of injury as well as the age of the patient. Direct trauma or a fall onto an outstretched hand is responsible for most elbow fractures. Neurovascular injury is a common complication of elbow fractures. The brachial artery is the most commonly injured artery and is seen especially in supracondylar fractures. The median nerve is the most commonly injured nerve, which is often is due to a displaced supracondylar humerus fracture. Extra-articular fracture patterns Intercondylar fractures (see Media file 1) - Intercondylar fractures occur when the condylar fragments are separated.
- They are much more common in adults than in children. Any distal humerus fracture in adults is more likely intercondylar than supracondylar.
- The mechanism is force directed against the posterior elbow such as a fall onto a flexed elbow, driving the olecranon against the humeral articular surface separating the condyles.
- Fractures are often a T or Y shaped fracture of the distal humerus.
- Treatment is often complicated and requires anatomic reduction either open or closed.2
Supracondylar fractures (see Media file 2) - The supracondylar fracture is the most common pediatric elbow fracture (60%) with the average age of 6.7 years and rarely seen after age 15 years.3
- Complications include injuries to nerves (the median, radial, and anterior interosseous nerves are the most commonly injured).
- Most deficits are neurapraxias that resolve with conservative management
- Motor function usually recovering in 7-12 weeks while sensory function usually recovers in 6 months.4
- Vascular injuries should always be suspected with supracondylar fractures.
- Ten percent of children have temporary loss of the radial pulse due to swelling and not direct arterial injury.5
- The most common complication for supracondylar fractures are cubitus varus or “gunstock deformity,” which is a loss of the carrying angle and results in more of a cosmetic disability rather than a functional disability (see Media file 9).
- Although rare (<0.5%), the most serious complication is Volkmann ischemic contracture due to postfracture swelling, producing increased pressure in the forearm compartment leading to muscle and nerve necrosis and eventual replacement by fibrotic tissue producing contracture.6
- In general, an orthopedic consultant best handles decisions regarding reduction of significantly angulated and displaced fractures.
- If neurovascular structures are compromised, the emergency physician may need to apply forearm traction to reestablish distal pulses.
- If pulse is not restored with traction, emergent operative intervention for brachial artery exploration or fasciotomy is indicated.
- In children, nondisplaced, nonangulated fractures can be splinted (elbow in 90° of flexion); angulated fractures require reduction and splinting; and displaced fractures (see Media file 3) require reduction and percutaneous pinning on an urgent basis within 12-24 hours.
- In adults, supracondylar fractures generally require surgery.
Extension-type - Ninety-five percent of supracondylar fractures are of the extension-type and are displaced posteriorly due to an extension force.
- Type I fractures - Undisplaced
- Type II fractures - Displaced with posterior cortex still intact
- Type III fractures - Displaced with both anterior and posterior cortex disrupted
- Management of type I fractures consists of immobilization with the elbow in flexion, while type II and II are generally treated by closed reduction followed by pin fixation.
- Type III fractures have significant displacement and have a high incidence of neurovascular injury and therefore require urgent orthopedic consultation in the ED.
- Open reduction is reserved for vascular insufficiency with a probable entrapped brachial artery in the fracture site or an irreducible fracture.
Flexion-type - Five percent of supracondylar fractures are of the flexion-type and have anterior displacement due to a flexion force.
- The mechanism usually involves direct anterior force with anterior displacement of the distal fragment.
- Open fractures are relatively common due to the direct force.
- Type I fractures - Undisplaced
- Type II fractures - Displaced with anterior cortex still intact
- Type III fractures - Displaced with both anterior and posterior cortex disrupted and distal fragment migrants anteriorly and proximately
- Treatment of type I fractures is simple immobilization in the flexed position.
- Treatment of type II and III fractures should be referred to an orthopedist emergently and is often reduced to an extension position and requires surgical management.5
Epicondyle fractures - Fractures of the epicondyles are considered extra-articular.
Medial epicondyle fracture (see Media file 4) - Medial epicondyle fractures are usually in children as an avulsion type injury
- Mechanisms include posterior elbow dislocation, throwing a baseball (Little League elbow), or a direct blow.
- Edema and pain over the medial elbow is common.
- Nondisplaced or minimally displaced medial epicondyle fractures are treated nonoperatively.
- Fragment displacement greater than 1 cm or valgus instability are often treated with internal fixation.
- Rarely, entrapment of the medial epicondyle can occur between the trochlea and the coronoid process of the ulna; this can be mistaken for the ossification center of the trochlea.
- ED management consists of immobilization of the forearm in flexion and pronation and the wrist in flexion.
Lateral epicondyle fracture - Lateral epicondyle fracture is very rare and is usually due to an avulsion fracture.
- Fracture of the lateral humeral epicondyle can be mistaken for the radiolucency of the epiphysis.7
- Treatment is immobilization with the elbow flexed to 90 degrees and the forearm in supination.7
Condyle fractures Medial condyle fracture - Medial condyle fracture is rare and is usually found in children.
- The mechanism is a fall on outstretched hand or excessive valgus stress.
- This injury is often confused with medial epicondyle fractures.
- Minimally displaced fractures are usually casted, whereas fractures with greater displacement usually require open or closed reduction with pin fixation.7
Lateral condyle fracture (see Media file 5) - Lateral condyle fracture is usually found in children and is the second most common pediatric elbow fracture.8
- The mechanism is a blow to the lateral elbow or from varus stress.
- Minimally displaced fractures are usually casted, whereas fractures with greater displacement usually require open or closed reduction with pin fixation.8
Intra-articular fracture patterns Trochlea fracture - Isolated trochlea fractures are rare and are usually associated with other elbow injuries.
- Nondisplaced fractures are usually managed with a posterior splint, whereas displaced fractures require surgical management.7
Capitellum fracture - Isolated capitellum fractures are rare as they often occur in posterior elbow dislocations or with radial head fractures.
- They are usually due to a fall on an outstretched hand.
- Surgical repair is often indicated.
Radial head fractures (see Media file 6) - Radial head fracture is the most common of all fractures of the elbow and associated injuries are common.
- The mechanism is usually a fall onto an outstretched hand.
- Radial head fracture is characterized by point tenderness at the radial head (located along the lateral aspect of the elbow) and pain with pronation/supination.
- A specific associated injury, the Essex-Lopresti lesion occurs when the radial-ulnar interosseous membrane is disrupted, causing distal radioulnar joint dissociation.
- Careful examination of radiographs is important because fractures may be subtle.
- For nondisplaced fractures, a sling with the elbow in flexion is usually adequate.
- With displaced radial head fractures, patients can be placed in a posterior long-arm splint with the elbow in 90° of flexion and the forearm in full supination and placed in a sling for comfort.
Olecranon fractures (see Media file 7) - The mechanism is usually a direct blow or a fall onto an outstretched hand.
- The fracture line is usually transverse, passing into the trochlear notch.7
- Patients demonstrate an inability to extend the elbow actively, along with point tenderness at the olecranon.
- Ulnar nerve injury is common.
- Patients can be placed in a well-padded, long-arm posterior splint with the elbow in 70° of flexion and the forearm neutral with respect to pronation/supination.
- Nondisplaced fractures are usually managed conservatively, whereas all others often require surgical repair.
Age
- Fracture patterns vary markedly among different age groups.
- Supracondylar fractures are the most common elbow fracture in children because of the relative strength of surrounding ligaments in comparison to bone.
- Radial head fractures are the most common elbow fracture in adults.
History
Mechanism of injury for most elbow fractures is direct elbow trauma or a fall onto an outstretched hand. Patients may experience the following:
- Pain
- Swelling
- Decreased range of motion
Physical
- A thorough neurovascular examination is vital in the assessment of elbow fractures because of the high incidence of neurovascular injuries with elbow fractures and the subsequent long-term complications with these injuries.
- With supracondylar fractures, the incidence of anterior interosseous nerve injury is high, and specific muscle testing of flexion at the distal interphalangeal joint of the index finger should be performed.9
- Patients often have decreased range of motion, and pain is present with pronation/supination of the forearm.
- Edema and ecchymosis near the elbow may be evident.
- Perform careful shoulder and wrist examinations with all elbow injuries.
Dislocations, Elbow
Fractures, Forearm
Fractures, Humerus
Pediatrics, Nursemaid Elbow
Imaging Studies
Anteroposterior (AP), lateral, and oblique radiographs of the elbow adequately visualize most elbow fractures.
To detect subtle elbow fractures, it is key to systematically view elbow films looking at certain aspects of the elbow.
- Anterior humeral line
- This is a line that is drawn along the anterior aspect of the humeral shaft on the lateral radiograph.
- The line passes through the middle one third of the capitellum in bones that are not injured.
- Only true lateral views should be used to assess this line.
- For example, a supracondylar fracture changes the anterior humeral line as it passes through the capitellum.
- Radiocapitellar line: This is a line that bisects the proximal radial shaft and should pass through the capitellum on every view.
- Fat pads (see Media file 8)
- On lateral films, the anterior fat pad normally lies against the anterior surface of the distal humerus.
- A joint effusion displaces this fat pad anteriorly and produces the sail sign.
- The posterior fat pad is not visible in films of the normal elbow; in patients with suspected elbow fracture, a posterior fat pad should be treated as a fracture.
- Fat pads may be elevated if fluid is present from other conditions such as joint infection or inflammation.
- Ossification centers
- Often, the pediatric elbow is difficult to evaluate due to the ossification centers of the elbow.
- One common mnemonic for the order of appearance for the ossification centers of the elbow is CRITOE:
| Ossification Centers | Age of Appearance, y | | Capitellum | 1-2 | | Radial head | 4-5 | | Internal (medial) epicondyle | 4-5 | | Trochlea | 8-10 | | Olecranon | 8-9 | | External (lateral) epicondyle | 10-11 |
Procedures
- In general, an orthopedic consultant best handles decisions regarding reduction of significantly angulated and displaced fractures.
- If neurovascular structures are compromised, the emergency physician may need to apply forearm traction to reestablish distal pulses.
- If pulse is not restored with traction, emergent operative intervention for brachial artery exploration or fasciotomy is indicated.
Emergency Department Care
- Emergency physicians need to do a thorough neurovascular examination as well as evaluate for concurrent injuries.
- Provide adequate analgesia to achieve patient comfort in the ED.
- Proper immobilization for the various types of elbow fractures is indicated.
- Assess whether the patient needs orthopedic evaluation in the ED, admission to the hospital for observation, or if discharge and follow up with an orthopedic surgeon is adequate.
Consultations
- All elbow fractures should be referred for orthopedic follow-up.
- Urgent orthopedic consultation in the ED is required in the following situations:
- If an open fracture or an open joint is suspected
- If the injury poses a significant risk of neurovascular injury such as a displaced supracondylar fracture
Drugs used to treat fractures are generally NSAIDs, analgesics, and anxiolytics. In addition, administer proper antibiotics and tetanus prophylaxis for open fractures.
Drug Category: Nonsteroidal anti-inflammatory agents (NSAIDs)
These drugs are used commonly for relief of mild to moderately severe pain. Effects of NSAIDs in treatment of pain tend to be patient specific, yet ibuprofen is usually DOC for initial therapy. Other options include flurbiprofen, ketoprofen, and naproxen.
| Drug Name | Ibuprofen (Ibuprin, Advil, Motrin) |
| Description | Usually DOC for treatment of mild to moderately severe pain, if no contraindications. Inhibits inflammatory reactions and pain, probably by decreasing activity of enzyme cyclooxygenase, which inhibits prostaglandin synthesis. |
| Adult Dose | 200-400 mg PO q4-6h prn; not to exceed 3.2 g/d |
| Pediatric Dose | <6 months: Not established 6 months to 12 years: 20-40 mg/kg/d PO divided tid/qid >12 years: Administer as in adults |
| Contraindications | Documented hypersensitivity; peptic ulcer disease; recent GI bleeding or perforation; renal insufficiency; high risk of bleeding |
| Interactions | Aspirin increases risk of inducing serious NSAID-related adverse effects; probenecid may increase concentrations and, possibly, toxicity; may decrease effects of hydralazine, captopril, and beta-blockers; may decrease diuretic effects of furosemide and thiazides; may increase PT in patients on anticoagulants—monitor PT closely and instruct patients to watch for signs of bleeding; may increase risk of methotrexate toxicity; may increase phenytoin levels |
| Pregnancy | B - Fetal risk not confirmed in studies in humans but has been shown in some studies in animals D - Fetal risk shown in humans; use only if benefits outweigh risk to fetus
|
| Precautions | Caution in congestive heart failure, hypertension, and decreased renal and hepatic function; caution in coagulation abnormalities or during anticoagulant therapy |
| Drug Name | Naproxen (Anaprox, Naprelan, Naprosyn) |
| Description | Used for relief of mild to moderately severe pain. Inhibits inflammatory reactions and pain by decreasing activity of enzyme cyclooxygenase, which decreases prostaglandin synthesis. |
| Adult Dose | 500 mg PO followed by 250 mg q6-8h; not to exceed 1.25 g/d |
| Pediatric Dose | <2 years: Not established >2 years: 5-7 mg/kg/dose PO q8-12h prn |
| Contraindications | Documented hypersensitivity; peptic ulcer disease; recent GI bleeding or perforation; renal insufficiency |
| Interactions | Aspirin increases risk of inducing serious NSAID-related adverse effects; probenecid may increase concentrations and, possibly, toxicity; may decrease effects of hydralazine, captopril, and beta-blockers; may decrease diuretic effects of furosemide and thiazides; may increase PT in patients taking anticoagulants—monitor PT closely and instruct patients to watch for signs of bleeding; may increase risk of methotrexate toxicity; may increase phenytoin levels |
| Pregnancy | B - Fetal risk not confirmed in studies in humans but has been shown in some studies in animals D - Fetal risk shown in humans; use only if benefits outweigh risk to fetus
|
| Precautions | Acute renal insufficiency, interstitial nephritis, hyperkalemia, hyponatremia, and renal papillary necrosis may occur; patients with preexisting renal disease or compromised renal perfusion risk acute renal failure; leukopenia occurs rarely, is transient, and usually returns to normal during therapy; persistent leukopenia, granulocytopenia, or thrombocytopenia warrants further evaluation and may require discontinuation of drug |
Drug Category: Analgesics
Pain control is essential to quality patient care. It ensures patient comfort, promotes pulmonary toilet, and aids physical therapy regimens. Many analgesics have sedating properties that benefit patients with fractures.
| Drug Name | Hydrocodone bitartrate and acetaminophen (Vicodin ES) |
| Description | Drug combination indicated for relief of moderately severe to severe pain. |
| Adult Dose | 1-2 tab/cap PO q4-6h prn |
| Pediatric Dose | <12 years: 750 mg acetaminophen PO q4h; single dose not to exceed 10 mg of hydrocodone bitartrate; not to exceed 5 doses/d >12 years: 10-15 mg/kg/dose acetaminophen q4-6h prn; not to exceed 2.6 g/d of acetaminophen |
| Contraindications | Documented hypersensitivity; high-altitude cerebral edema; elevated intracranial pressure |
| Interactions | Phenothiazines may decrease analgesic effects; CNS depressants or tricyclic antidepressants may increase toxicity |
| Pregnancy | C - Fetal risk revealed in studies in animals but not established or not studied in humans; may use if benefits outweigh risk to fetus
|
| Precautions | Tablets contain metabisulfite, which may cause hypersensitivity; caution in patients dependent on opiates because this substitution may result in acute opiate-withdrawal symptoms; caution in severe renal or hepatic dysfunction |
| Drug Name | Oxycodone and acetaminophen (Percocet) |
| Description | Drug combination indicated for relief of moderately severe to severe pain. DOC for aspirin-hypersensitive patients. |
| Adult Dose | 1-2 tab/cap PO q4-6h prn |
| Pediatric Dose | 0.05-0.15 mg/kg/dose oxycodone PO q4-6h prn; not to exceed 5 mg/dose of oxycodone |
| Contraindications | Documented hypersensitivity |
| Interactions | Phenothiazines may decrease analgesic effects; CNS depressants or tricyclic antidepressants may increase toxicity |
| Pregnancy | C - Fetal risk revealed in studies in animals but not established or not studied in humans; may use if benefits outweigh risk to fetus
|
| Precautions | Duration of action may increase in elderly persons; be aware of total daily dose of acetaminophen patient is receiving; do not exceed 4000 mg/24h of acetaminophen; higher doses may cause liver toxicity |
Drug Category: Anxiolytics
Patients with painful injuries usually experience significant anxiety. Anxiolytics allow a smaller analgesic dose to achieve the same effect.
| Drug Name | Lorazepam (Ativan) |
| Description | Sedative hypnotic in benzodiazepine class that has a short onset of effect and relatively long half-life. By increasing action of GABA, a major inhibitory neurotransmitter, may depress all levels of CNS, including limbic and reticular formation. Excellent for sedating patient for longer than 24-h period. Monitor patient's BP after administering dose and adjust as necessary. |
| Adult Dose | Initial dose: 2 mg total or 0.044 mg/kg IV, whichever is smaller |
| Pediatric Dose | 0.05-0.1 mg/kg IV slowly q2-5min; may repeat dose of 0.05 mg/kg IV slowly |
| Contraindications | Documented hypersensitivity; preexisting CNS depression; hypotension; narrow-angle glaucoma |
| Interactions | Alcohol, phenothiazines, barbiturates, and MAOIs increase CNS toxicity |
| Pregnancy | D - Fetal risk shown in humans; use only if benefits outweigh risk to fetus
|
| Precautions | Caution in renal or hepatic impairment, myasthenia gravis, organic brain syndrome, or Parkinson disease |
Drug Category: Antibiotics
These agents are given as prophylaxis to patients with open fractures.
| Drug Name | Cefazolin (Ancef) |
| Description | Used along with gentamicin for prophylaxis in patients with open fractures. First-generation semisynthetic cephalosporin that by binding to 1 or more penicillin-binding proteins arrests bacterial cell wall synthesis and inhibits bacterial replication. Poor capacity to cross blood-brain barrier. Primarily active against skin flora, including S aureus. Typically used alone for skin and skin-structure coverage. IV and IM dosing regimens are similar. |
| Adult Dose | 1 g IV/IM q6-8h |
| Pediatric Dose | 25-100 mg/kg/d IV/IM divided q6-8h depending on severity of infection; not to exceed 6 g/d |
| Contraindications | Documented hypersensitivity |
| Interactions | Probenecid prolongs effect of cefazolin; coadministration with aminoglycosides may increase renal toxicity; may yield false-positive urine-dip test results for glucose |
| Pregnancy | B - Fetal risk not confirmed in studies in humans but has been shown in some studies in animals
|
| Precautions | Adjust dose in severe renal insufficiency (high doses may cause CNS toxicity); superinfections and promotion of nonsusceptible organisms may occur with prolonged use or repeated therapy |
| Drug Name | Gentamicin (Gentacidin, Garamycin) |
| Description | Aminoglycoside antibiotic used for gram-negative bacterial coverage. Commonly used in combination with both an agent against gram-positive organisms and one that covers anaerobes. Dosing regimens are numerous and adjusted based on renal function (CrCl) and changes in volume of distribution. Dose may be given IV/IM. |
| Adult Dose | 1.5 mg/kg/dose IV q8-24h; not to exceed 80 mg; may need dosage adjustment in patients with renal impairment |
| Pediatric Dose | <5 years with normal renal function: 2.5 mg/kg/dose q8h IV/IM >5 years: 1.5-2.5 mg/kg/dose IV/IM q8h or 6-7.5 mg/kg/d q8h; not to exceed 300 mg/d, with adjustments for renal function prn; monitor levels as in adults |
| Contraindications | Documented hypersensitivity; non–dialysis-dependent renal insufficiency |
| Interactions | Other aminoglycosides, cephalosporins, penicillins, and amphotericin B may increase nephrotoxicity; enhances effects of neuromuscular blocking agents and thus may cause prolonged respiratory depression; loop diuretics may increase auditory toxicity—possible irreversible hearing loss of varying degrees may occur (monitor regularly) |
| Pregnancy | C - Fetal risk revealed in studies in animals but not established or not studied in humans; may use if benefits outweigh risk to fetus
|
| Precautions | Narrow therapeutic index (not intended for long-term therapy); caution in renal failure (not on dialysis), myasthenia gravis, hypocalcemia, and conditions that depress neuromuscular transmission; adjust dose in renal impairment |
Drug Category: Toxoid
This agent is used for tetanus immunization. Booster injection in previously immunized individuals is recommended to prevent this potentially lethal syndrome.
| Drug Name | Tetanus toxoid |
| Description | Induces active immunity against tetanus in selected patients. Immunizing DOC for most adults and children >7 y are tetanus and diphtheria toxoids. Necessary to administer booster doses to maintain tetanus immunity throughout life. Pregnant patients should receive only tetanus toxoid, not a diphtheria antigen-containing product. In children and adults, may administer into deltoid or midlateral thigh muscles. In infants, preferred site of administration is midthigh, lateral. |
| Adult Dose | Primary immunization: 0.5 mL IM, give 2 injections q4-8 wk apart and a third dose q6-12 mo after second injection Booster dose: 0.5 mL q10y |
| Pediatric Dose | Administer as in adults |
| Contraindications | Documented hypersensitivity; history of any type of neurological symptoms or signs following administration of this product FDA recommends that elective tetanus immunization be deferred during any outbreak of poliomyelitis because tetanus toxoid injections are an important cause of provocative poliomyelitis |
| Interactions | Patients receiving immunosuppressants, including corticosteroids or radiation therapy, may remain susceptible despite immunization due to poor immune response; cimetidine may enhance or augment delayed-hypersensitivity responses to skin-test antigens; avoid concurrent use of chloramphenicol since it may impair amnestic response to tetanus toxoid; concurrent use of tetanus immune globulin may delay development of active immunity by several days (interaction is nevertheless clinically insignificant and does not preclude its concurrent use) |
| Pregnancy | C - Fetal risk revealed in studies in animals but not established or not studied in humans; may use if benefits outweigh risk to fetus
|
| Precautions | Do not use to treat actual tetanus infections or for immediate prophylaxis of unimmunized individuals (use instead tetanus antitoxin, preferably human tetanus immune globulin); diminished antibody response to active immunization may be seen in patients receiving immunosuppressive therapy; better to defer primary diphtheria immunization until immunosuppressive therapy discontinued; routine immunization of symptomatic and asymptomatic HIV-infected persons is recommended |
Drug Category: Immunoglobulins
Patients who may not have been immunized against Clostridium tetani products should receive tetanus immune globulin.
| Drug Name | Tetanus immune globulins (Hyper-Tet) |
| Description | For passive immunization of any person with a wound that may be contaminated with tetanus spores. |
| Adult Dose | For prophylaxis: 250-500 U IM in opposite extremity to tetanus toxoid For clinical tetanus: 3,000-10,000 U IM |
| Pediatric Dose | For prophylaxis: 250 U IM in opposite extremity to tetanus toxoid For clinical tetanus: 3,000-10,000 U IM |
| Contraindications | Because antibodies in globulin preparation may interfere with immune response to vaccination, do not administer within 3 mo of live-virus immune globulin administration; may be necessary to revaccinate persons who received immune globulin shortly after live-virus vaccination |
| Interactions | None reported |
| Pregnancy | C - Fetal risk revealed in studies in animals but not established or not studied in humans; may use if benefits outweigh risk to fetus
|
| Precautions | Persons with isolated IgA deficiency have potential for developing antibodies to IgA and could have anaphylactic reactions to subsequent administration of blood products that contain IgA; do not perform skin testing since intradermal injection of concentrated gamma globulin may cause localized area of inflammation and can be misinterpreted, causing the medication to be withheld from a patient not allergic to this material; true allergic responses to human gamma globulin given in prescribed IM manner are extremely rare; do not admix with other medications since usually incompatible |
Further Inpatient Care
- Open fractures require extensive irrigation and appropriate prophylactic antibiotics, such as cefazolin and gentamicin.
- Displaced supracondylar fractures require surgical intervention and continual monitoring of neurovascular status.
Further Outpatient Care
- Supracondylar fracture
- Refer patients with nondisplaced fractures to an orthopedist within 24 hours to evaluate and recheck neurovascular status.
- Upon dissipation of edema, apply a long-arm cast that holds the elbow in 90° of flexion for approximately 6 weeks.
- Radial head fracture
- For uncomplicated fractures, begin range of motion exercises within 3-7 days to reduce the risk of permanent loss of motion from elbow joint contracture.
- Intra-articular fractures, which may require radial head excision or fixation, should be seen by an orthopedist within 1 week for definitive management.
- Olecranon fracture: Nonoperative fractures (minimally displaced with an intact extensor mechanism) can be treated with a splint and range of motion exercises within a few weeks.
In/Out Patient Meds
- As with all fractures, address adequate outpatient analgesia, especially during the first few days.
- Acetaminophen, with codeine or hydrocodone, may be appropriate treatment.
Complications
- Supracondylar fracture
- Cubitus varus: The most common complication for supracondylar fractures are cubitus varus or “gunstock deformity,” which is a loss of the carrying angle and results in more of a cosmetic disability rather than a functional disability (see Media file 8).
- Volkmann ischemia: This is a form of compartment syndrome that can lead to muscle ischemia and permanent muscle contracture, particularly occurring in children. Symptoms suggestive of this complication include pain with passive extension of the fingers, refusal to open the hand, and forearm tenderness.
- Median nerve injury: Displaced supracondylar humerus fractures may lead to median nerve dysfunction. Rarely does this result in complete nerve transection, and full return of function is common.
- Malunion: Angulated or displaced fractures that remain unreduced lead to functional and cosmetic deformities.
- Radial head fracture
- Nondisplaced fractures that are immobilized for prolonged periods of time may have permanently decreased range of motion.
- Comminuted radial head fractures associated with undiagnosed distal radial-ulnar joint injuries can lead to permanent wrist injuries and loss of pronation/supination motion.
- Olecranon fracture: An ulnar nerve injury, although rare, may be associated with a displaced olecranon fracture.
Prognosis
- Supracondylar fracture
- Children: Undisplaced fractures and properly managed displaced/angulated fractures result in no long-term functional deficits.
- Adults: Usually, range of motion decreases somewhat but without functional deficit.
- Radial head fracture: Usually, no functional loss occurs with nonoperative treatment.
- Olecranon fracture
- This fracture may result in loss of full extension but usually restores strength.
- Olecranon fracture can be associated with posttraumatic arthritis of the elbow.
- Most operative and nonoperative cases of olecranon fracture have a good outcome with no long-term deficits.
Patient Education
Medical/Legal Pitfalls
- Failure to document a neurovascular examination in a child with a supracondylar fracture
- Failure to reexamine and document neurovascular examination following application of a splint, elbow flexion greater than 90° may obliterate pulse or compromise neurologic function
- Failure to pad the olecranon when splinting an olecranon fracture may lead to skin breakdown and iatrogenic open fracture
- Failure to maintain prolonged immobilization of radial head fractures leads to permanently decreased range of motion
- Failure to recognize a radial head dislocation associated with a fracture of the proximal ulna (Monteggia fracture or dislocation)
Thank you Sabrina Sakata for your editing and encouragement.
| Media file 8:
Anterior and posterior fat pads with radial head fracture. |
 | View Full Size Image | |
Media type: Radiograph
|
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Fracture, Elbow excerpt Article Last Updated: Jul 10, 2008
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