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Excerpt from Pityriasis RoseaSynonyms, Key Words, and Related Terms: pityriasis rosea, PR, pityriasis rosea gigantica, pityriasis rosea urticata, papular PR, atypical PR, drug-induced PR, keratosis, vesicular PR, herald patch, rash, pruritus, exanthem Please click here to view the full topic text: Pityriasis RoseaBackgroundPityriasis rosea (PR) is an acute and characteristic exanthem that has been described for more than 2 centuries. Initially, a primary plaque, called a herald patch, is seen. The herald patch is followed by a distinctive, generalized rash 1-2 weeks later. The rash lasts approximately 2-6 weeks. PathophysiologyThe primary plaque is seen on the skin in 50-90% of cases a week or more before the onset of the eruption of smaller lesions. This secondary eruption occurs 2-21 days later in crops following the lines of cleavage of the skin. On the back, this eruption produces a "Christmas tree" pattern. FrequencyUnited StatesThe overall prevalence of PR has been calculated to be 0.13% in men and 0.14% in women. The prevalence reported at dermatologic centers has been between 0.3 and 3%. InternationalAn increase in the prevalence of PR has been reported in Uganda. No change in the prevalence of PR has been reported in Sweden. It has also been seen in the United Kingdom, Nigeria, Sudan, Brazil, Lagos, Singapore, Turkey, Kuwait, and Hong Kong. Mortality/MorbidityPR is a self-limited benign illness. SexPR is reported to occur equally in the two sexes or slightly more often in females. The ratio of men to women varies from 1:1.43. AgePR is most common in children and young adults. Prevalence of PR rises during childhood and is most common in persons aged 15-40 years. PR is rare in infants and in elderly persons; however, it has been reported in infants as young as 3 months. Please click here to view the full topic text: Pityriasis Rosea |
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