Continually Updated Clinical Reference
 
 
  All Sources     eMedicine     Medscape     Drug Reference     MEDLINE
 
eMedicine - Stucco Keratosis : Article by

Quick Find
Authors & Editors
Introduction
Clinical
Differentials
Workup
Treatment
Medication
Follow-up
Miscellaneous
Multimedia
References

Related Articles
Acrokeratosis Verruciformis of Hopf




Patient Education
Click here for patient education.



Author: Raymond T Kuwahara, MD, Dermatologist, Private Practice

Raymond T Kuwahara is a member of the following medical societies: American Academy of Dermatology

Coauthor(s): Ron Rasberry, MD, Chief of Dermatology, Veterans Medical Center at Memphis; Associate Professor, Department of Dermatology, University of Tennessee at Memphis

Editors: Evan R Farmer, MD, Professor of Dermatology, Johns Hopkins University School of Medicine, Clinical Professor of Pathology, Virginia Commonwealth University School of Medicine; Consulting Staff, Department of Dermatology, Johns Hopkins Hospital, VCU Health Services; Richard P Vinson, MD, Assistant Clinical Professor, Department of Dermatology, Texas Tech University School of Medicine; Consulting Staff, Mountain View Dermatology, PA; Warren R Heymann, MD, Head, Division of Dermatology, Professor, Department of Internal Medicine, University of Medicine and Dentistry of New Jersey; Joel M Gelfand, MD, MSCE, Medical Director, Clinical Studies Unit, Assistant Professor, Department of Dermatology, Associate Scholar, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania; Dirk M Elston, MD, Director, Department of Dermatology, Geisinger Medical Center

Author and Editor Disclosure

Synonyms and related keywords: verruca dorsimanus et pedis

Background

Stucco keratosis was first described by Kocsard and Ofner in 1965 and later by Willoughby and Soter in 1972.

Stucco keratosis is a keratotic papule that is usually found on the distal lower acral extremities of males. It seems to appear with a higher frequency in males; however, it is not inherited genetically.

Usually, multiple lesions are found; in one study, between 7 and more than 100 lesions were noted on the patients. The lesion is asymptomatic, and patients usually do not complain of having the lesions. The name stucco keratosis is derived from the "stuck on" appearance of the lesions.

Pathophysiology

Stucco keratosis appears to be produced by thickening of the epidermis. The epidermis is usually exophytic with a church spire–like appearance. The surface may be regularly distributed into folds with elongation of papillae. The stratum corneum is thickened.

Surface friction may contribute to the development of the lesions. The tumor grows outward and does not penetrate. The lesions are usually found in elderly patients.

With a nested polymerase chain reaction technique, human papillomavirus types 9, 16, 23b, DL322, and 37 were detected in a 75-year-old nonimmunosuppressed man with very extensive lesions. This finding requires confirmation in other patients.

Frequency

United States

The incidence of stucco keratosis is about 10% of the senior population in the United States. It predominantly occurs in elderly men.

Mortality/Morbidity

  • The lesions are benign growths similar to those of seborrheic keratosis.
  • Clinically, they may be mistaken as a melanoma.

Race

  • Stucco keratosis is found in persons of all races.
  • No reports have been noted on race as a factor in this lesion.

Sex

  • The incidence is higher in males than in females.

Age

  • Elderly people are susceptible to the disease.
  • The lesions begin to appear around age 45 years.



History

  • Stucco keratosis is a benign lesion that is best regarded as a form of seborrheic keratosis.
  • These lesions are often seen in elderly men.
  • The lesions are asymptomatic and usually go unnoticed by both the patient and the clinician.

Physical

  • The lesion appears as a keratotic papule or plaque on the lower extremities but is sometimes found on the upper extremities, usually acrally (see Media File 1).
  • If the lesion is removed by curetting, a peripheral collarette of scale is sometimes left.

Causes

  • No known cause has been reported.
  • The epidermis is hyperplastic and usually exophytic with no dysplasia. This is similar to what is seen in seborrheic keratosis.



Acrokeratosis Verruciformis of Hopf

Other Problems to be Considered

Hard nevus of Unna has a similar histopathologic feature of a saw tooth epidermis. The term hard nevus is not used anymore in the literature but could be a term that includes what is described as stucco keratosis.



Lab Studies

No laboratory studies are required.

Imaging Studies

No imaging studies are required.

Procedures

Different methods or a combination of methods can be used to remove the lesions. The most common methods in practice are liquid nitrogen therapy and curettage.

  • Liquid nitrogen therapy
    • Lesions can be frozen with liquid nitrogen by either the spray method or the dipstick method. Because the lesions are benign, the required temperature of the lesion should reach -25°C.
    • Depending on the thickness of the lesion, 2 freeze cycles of 3-10 seconds are usually required. The lesions fall off in a few days, and, if the procedure is not successful, liquid nitrogen therapy may be repeated. Ambient temperature and skin temperature as well as underlying vascularity must be taken into account. Ulceration can occur if cryotherapy is too vigorous.
  • Curettage
    • Stucco keratosis can be removed by curettage. Lesions can be removed by gentle scraping.
    • Once the lesion is removed, a topical antibiotic can be applied.
  • Other methods that can be used include the following:
    • The lesion can be removed by using an electrodesiccator.
    • Shave removal is performed only if the lesion appears malignant, does not scrape off, or requires a definitive diagnosis.

Histologic Findings

A church spire–like epidermal hyperplasia similar to that in hyperkeratotic seborrheic keratosis is seen (see Media File 2).



Medical Care

Stucco keratosis is a benign lesion that can be removed by curettage or cryotherapy. No other medical care is required.

Surgical Care

No surgical care is required.



No medical therapy is required.



Further Outpatient Care

Patients should be advised to have a periodic skin examination.

Patient Education

Patients can be informed that the lesions are not cancerous. Because lesions are found in elderly patients, the patients can be taught the "ABCDs" of melanoma.



Medical/Legal Pitfalls

A biopsy should be performed on lesions that do not scrape off easily or have unusual colors if the clinical diagnosis is not clear. Squamous cell carcinomas and possibly melanomas can look like stucco keratosis.



Media file 1:  Stucco keratosis in a 70-year-old male veteran. A few scattered white plaques are on the lower extremity.
Click to see larger pictureClick to see detailView Full Size Image
Media type:  Photo

Media file 2:  Photomicrograph of characteristic church spires of stucco keratosis.
Click to see larger pictureClick to see detailView Full Size Image
Media type:  Photo



  • Kirkham N. Tumors and cysts of the epidermis. In: Lever's Histopathology of the Skin. Philadelphia, Pa: WB Saunders; 1997:693.
  • Kocsard E, Carter JJ. The papillomatous keratoses. The nature and differential diagnosis of stucco keratosis. Australas J Dermatol. Aug 1971;12(2):80-8. [Medline].
  • Stockfleth E, Röwert J, Arndt R, Christophers E, Meyer T. Detection of human papillomavirus and response to topical 5% imiquimod in a case of stucco keratosis. Br J Dermatol. Oct 2000;143(4):846-50. [Medline].
  • Waisman M. Verruciform manifestations of keratosis follicularis: including a reappraisal of hard nevi (Unna). Arch Dermatol. 1960;81:1-15.
  • Willoughby C, Soter NA. Stucco keratosis. Arch Dermatol. Jun 1972;105(6):859-61. [Medline].

Stucco Keratosis excerpt

Article Last Updated: Oct 17, 2007