Sakuntabhai A, Ruiz-Perez V, Carter S, et al. Mutations in ATP2A2, encoding a Ca2+ pump, cause Darier disease. Nat Genet. 1999 Mar. 21(3):271-7. [QxMD MEDLINE Link].
Ronan A, Ingrey A, Murray N, Chee P. Recurrent ATP2A2 p.(Pro602Leu) mutation differentiates Acrokeratosis verruciformis of Hopf from the allelic condition Darier disease. Am J Med Genet A. 2017 May 12. [QxMD MEDLINE Link].
Onozuka T, Sawamura D, Yokota K, Shimizu H. Mutational analysis of the ATP2A2 gene in two Darier disease families with intrafamilial variability. Br J Dermatol. 2004 Apr. 150(4):652-7. [QxMD MEDLINE Link].
Bchetnia M, Charfeddine C, Kassar S, Zribi H, Guettiti HT, Ellouze F. Clinical and mutational heterogeneity of Darier disease in Tunisian families. Arch Dermatol. 2009 Jun. 145(6):654-6. [QxMD MEDLINE Link].
Shi HJ, Li M, Zhang GL, et al. Novel splice-site and frameshift ATP2A2 mutations in Chinese patients with Darier disease. Clin Exp Dermatol. 2012. [QxMD MEDLINE Link].
Folster-Holst R, Nellen RG, Jensen JM, et al. Molecular genetic support for the rule of dichotomy in type 2 segmental Darier disease. Br J Dermatol. Feb 2012. 166:464-6. [QxMD MEDLINE Link].
Wang Y, Bruce AT, Tu C, et al. Protein aggregation of SERCA2 mutants associated with Darier disease elicits ER stress and apoptosis in keratinocytes. J Cell Sci. Nov 2011. 124:3568-80. [QxMD MEDLINE Link].
Harboe TL, Willems P, Jespersgaard C, et al. Mosaicism in segmental Darier disease: an in-depth molecular analysis quantifying proportions of mutated alleles in various tissues. Dermatology. Jul 2011. 222:292-6. [QxMD MEDLINE Link].
Pedace L, Barboni L, Pozzetto E, Amantea A, Zambruno G, Preziosi N, et al. Molecular characterization of 11 Italian patients with Darier disease. Eur J Dermatol. May-Jun 2011. 21:334-8. [QxMD MEDLINE Link].
Klausegger A, Nischler E, Wagner RN, Pletschacher F, Hintner H, Bauer JW. Seven novel mutations in the ATP2A2 gene of Austrian patients with Darier's disease. Arch Dermatol Res. 2011 Jul. 303(5):371-4. [QxMD MEDLINE Link].
Godic A, Strazisar M, Zupan A, Korosec B, Kansky A, Glavac D. Darier disease in Slovenia: spectrum of ATP2A2 mutations and relation to patients' phenotypes. Eur J Dermatol. 2010 May-Jun. 20(3):271-5. [QxMD MEDLINE Link].
Li CR, Cui PG, Jia H, et al. Identification of a novel mutation in a Chinese patient with mild Darier’s disease. Int J Dermatol. Nov 2010. 49:1286-8. [QxMD MEDLINE Link].
Huo J, Liu Y, Ma J, Xiao S. A novel splice-site mutation of ATP2A2 gene in a Chinese family with Darier disease. Arch Dermatol Res. Dec 2010. 302:769-72. [QxMD MEDLINE Link].
Lu FY, Xu L, Yin XG, Wan P, Zhang XD, Chen WW, et al. Identification of mutation c.632G>A (p.G211D) in the ATP2A2 gene and genotype-phenotype correlation in a large Chinese family with Darier's disease. Int J Dermatol. 2011 Nov. 50(11):1366-70. [QxMD MEDLINE Link].
Shi HJ, Li M, Zhang GL, Xu SX, Shao MH, Gu Y, et al. Novel splice-site and frameshift ATP2A2 mutations in Chinese patients with Darier disease. Clin Exp Dermatol. 2012 Aug. 37(6):677-9. [QxMD MEDLINE Link].
Shi BJ, Xue M, Zhong GS, Jiang Y, Chen DY, Feng J, et al. The ATP2A2 gene in patients with Darier's disease: one novel splicing mutation. Int J Dermatol. 2012 Sep. 51(9):1074-7. [QxMD MEDLINE Link].
Ueo D, Hamada T, Hashimoto T, Hatano Y, Okamoto O, Fujiwara S. Late-onset Darier's disease due to a novel missense mutation in the ATP2A2 gene: a different missense mutation affecting the same codon has been previously reported in acrokeratosis verruciformis. J Dermatol. 2013 Apr. 40(4):280-1. [QxMD MEDLINE Link].
Green EK, Gordon-Smith K, Burge SM, Grozeva D, Munro CS, Tavadia S, et al. Novel ATP2A2 mutations in a large sample of individuals with Darier disease. J Dermatol. 2013 Apr. 40(4):259-66. [QxMD MEDLINE Link].
Pengjun Z, Jianwen R, Biao Y. A novel missense mutation of ATP2A2 gene in a Chinese family with Darier disease. Int J Dermatol. 2014 Mar. 53(3):e204-5. [QxMD MEDLINE Link].
Miyabe C, Mitsuhashi Y, Saito M, Tsuboi R. Novel mutation in the ATP2A2 gene in a Japanese Darier's disease patient with extremely hyperkeratotic lesions. J Dermatol. 2012 Apr. 39(4):401-3. [QxMD MEDLINE Link].
Shi BJ, Xue M, Zhu YJ, Wang SP, Du Y, Chen DY, et al. Exon 12 of the ATP2A2 gene in patients with Darier disease: one novel mutation and one previously described. J Eur Acad Dermatol Venereol. 2014 Feb 19. [QxMD MEDLINE Link].
Miyauchi Y, Daiho T, Yamasaki K, Takahashi H, Ishida-Yamamoto A, Danko S. Comprehensive analysis of expression and function of 51 sarco(endo)plasmic reticulum Ca2+-ATPase mutants associated with Darier disease. J Biol Chem. 2006 Aug 11. 281(32):22882-95. [QxMD MEDLINE Link].
Müller EJ, Caldelari R, Kolly C, Williamson L, Baumann D, Richard G, et al. Consequences of depleted SERCA2-gated calcium stores in the skin. J Invest Dermatol. 2006 Apr. 126(4):721-31. [QxMD MEDLINE Link].
Kassar S, Tounsi-Kettiti H, Charfeddine C, Zribi H, Bchetnia M, Jerbi E, et al. Histological characterization of Darier's disease in Tunisian families. J Eur Acad Dermatol Venereol. 2009 Oct. 23(10):1178-83. [QxMD MEDLINE Link].
Dhitavat J, Fairclough RJ, Hovnanian A, Burge SM. Calcium pumps and keratinocytes: lessons from Darier's disease and Hailey-Hailey disease. Br J Dermatol. 2004 May. 150(5):821-8. [QxMD MEDLINE Link].
Dhitavat J, Cobbold C, Leslie N, Burge S, Hovnanian A. Impaired trafficking of the desmoplakins in cultured Darier's disease keratinocytes. J Invest Dermatol. 2003 Dec. 121(6):1349-55. [QxMD MEDLINE Link].
Leinonen PT, Hägg PM, Peltonen S, Jouhilahti EM, Melkko J, Korkiamäki T, et al. Reevaluation of the normal epidermal calcium gradient, and analysis of calcium levels and ATP receptors in Hailey-Hailey and Darier epidermis. J Invest Dermatol. 2009 Jun. 129(6):1379-87. [QxMD MEDLINE Link].
Celli A, Mackenzie DS, Zhai Y, Tu CL, Bikle DD, Holleran WM, et al. SERCA2-controlled Ca²+-dependent keratinocyte adhesion and differentiation is mediated via the sphingolipid pathway: a therapeutic target for Darier's disease. J Invest Dermatol. 2012 Apr. 132(4):1188-95. [QxMD MEDLINE Link]. [Full Text].
Savignac M, Simon M, Edir A, Guibbal L, Hovnanian A. SERCA2 Dysfunction in Darier Disease Causes Endoplasmic Reticulum Stress and Impaired Cell-to-Cell Adhesion Strength: Rescue by Miglustat. J Invest Dermatol. 2014 Jul. 134(7):1961-70. [QxMD MEDLINE Link].
Fong G, Capaldi L, Sweeney SM, Wiss K, Mahalingam M. Congenital Darier disease. J Am Acad Dermatol. 2008 Aug. 59(2 Suppl 1):S50-1. [QxMD MEDLINE Link].
Matsumoto A, Gregory N, Rady PL, Tyring SK, Carlson JA. Brief Report: HPV-17 Infection in Darier Disease With Acrokeratosis Verrucosis of Hopf. Am J Dermatopathol. 2017 May. 39 (5):370-373. [QxMD MEDLINE Link].
Okada E, Nagai Y, Motegi S, Tamura A, Ishikawa O. Fatal case of Darier's disease with recurrent severe infections. Acta Derm Venereol. 2009. 89(4):408-9. [QxMD MEDLINE Link].
Woo SM, Won CH, Cho S. Darier's disease: variable clinical presentation and a fatal outcome. Clin Exp Dermatol. 2009 Jul. 34(5):628-9. [QxMD MEDLINE Link].
Tang C, Chan M, Lee J, Hariram J. Darier's disease and schizophrenia. East Asian Arch Psychiatry. 2010 Dec. 20(4):190-2. [QxMD MEDLINE Link].
Dodiuk-Gad RP, Cohen-Barak E, Khayat M, Milo H, Amariglio-Diskin L, Danial-Faran N, et al. Darier disease in Israel: combined evaluation of genetic and neuropsychiatric aspects. Br J Dermatol. 2016 Mar. 174 (3):562-8. [QxMD MEDLINE Link].
Cederlöf M, Bergen SE, Långström N, Larsson H, Boman M, Craddock N, et al. The association between Darier disease, bipolar disorder, and schizophrenia revisited: a population-based family study. Bipolar Disord. 2015 May. 17 (3):340-4. [QxMD MEDLINE Link].
Cederlöf M, Karlsson R, Larsson H, Almqvist C, Magnusson PK, Nordlind K, et al. Intellectual disability and cognitive ability in Darier disease: Swedish nation-wide study. Br J Dermatol. 2015 Jul. 173 (1):155-8. [QxMD MEDLINE Link].
Otley CC, Momtaz K. Induction of Darier-White disease with UVB radiation in a clinically photo-insensitive patient. J Am Acad Dermatol. 1996 May. 34(5 Pt 2):931-4. [QxMD MEDLINE Link].
Bernabé DG, Kawata LT, Beneti IM, Crivelini MM, Biasoli ER. Multiple white papules in the palate: oral manifestation of Darier's disease. Clin Exp Dermatol. 2009 Oct. 34(7):e270-1. [QxMD MEDLINE Link].
Kansal NK, Hazarika N, Rao S. Familial Case of Darier Disease with Guttate Leukoderma: A Case Series from India. Indian Dermatol Online J. 2018 Jan-Feb. 9 (1):62-63. [QxMD MEDLINE Link].
Matsuoka LY, Wortsman J. Renal involvement in Darier disease. J Am Acad Dermatol. 2016 Dec. 75 (6):e235. [QxMD MEDLINE Link].
Mansura A, Maly A, Ramot Y, Zlotogorski A. Acantholytic dermatosis of the vulva. Dermatol Online J. 2015 May 18. 21 (5):[QxMD MEDLINE Link].
Ashok Kumar P, Paulraj S, Dutta S. Debilitating Darier's Disease and Its Impact on the Quality of Life. Cureus. 2020 May 15. 12 (5):e8133. [QxMD MEDLINE Link].
Tolaymat L, Zito PM. Adapalene. StatPearls [Internet]. 2020 Jan. [QxMD MEDLINE Link]. [Full Text].
Bachar-Wikstrom E, Curman P, Ahanian T, Leong IUS, Larsson H, Cederlöf M, et al. Darier disease is associated with heart failure: a cross-sectional case-control and population based study. Sci Rep. 2020 Apr 23. 10 (1):6886. [QxMD MEDLINE Link].
Casals M, Campoy A, Aspiolea F, Carrasco MA, Camps A. Successful treatment of linear Darier's disease with topical adapalene. J Eur Acad Dermatol Venereol. 2009 Feb. 23(2):237-8. [QxMD MEDLINE Link].
Abe M, Inoue C, Yokoyama Y, Ishikawa O. Successful treatment of Darier's disease with adapalene gel. Pediatr Dermatol. 2011 Mar-Apr. 28(2):197-8. [QxMD MEDLINE Link].
Burkhart CG, Burkhart CN. Tazarotene gel for Darier's disease. J Am Acad Dermatol. 1998 Jun. 38(6 Pt 1):1001-2. [QxMD MEDLINE Link].
Oster-Schmidt C. The treatment of Darier's disease with topical tazarotene. Br J Dermatol. 1999 Sep. 141(3):603-4. [QxMD MEDLINE Link].
Dicken CH, Bauer EA, Hazen PG, Krueger GG, Marks JG Jr, McGuire JS, et al. Isotretinoin treatment of Darier's disease. J Am Acad Dermatol. 1982 Apr. 6(4 Pt 2 Suppl):721-6. [QxMD MEDLINE Link].
Schmidt H, Ochsendorf FR, Wolter M, Geisslinger G, Ludwig RJ, Kaufmann R. Topical 5-fluorouracil in Darier disease. Br J Dermatol. 2008 Jun. 158(6):1393-6. [QxMD MEDLINE Link].
Yoon TY, Kim JW, Kim MK. Successful treatment of Darier disease with topical 5-fluorouracil. Br J Dermatol. 2006 Jun. 154(6):1210-2. [QxMD MEDLINE Link].
Abe M, Yasuda M, Yokoyama Y, Ishikawa O. Successful treatment of combination therapy with tacalcitol lotion associated with sunscreen for localized Darier's disease. J Dermatol. 2010 Aug. 37(8):718-21. [QxMD MEDLINE Link].
Pérez-Carmona L, Fleta-Asín B, Moreno-García-Del-Real C, Jaén-Olasolo P. Successful treatment of Darier's disease with topical pimecrolimus. Eur J Dermatol. 2011 Mar-Apr. 21(2):301-2. [QxMD MEDLINE Link].
Millán-Parrilla F, Rodrigo-Nicolás B, Molés-Poveda P, Armengot-Carbó M, Quecedo-Estébanez E, Gimeno-Carpio E. Improvement of Darier disease with diclofenac sodium 3% gel. J Am Acad Dermatol. 2014 Apr. 70(4):e89-90. [QxMD MEDLINE Link].
Kontochristopoulos G, Katsavou AN, Kalogirou O, Agelidis S, Zakopoulou N. Letter: Botulinum toxin type A: an alternative symptomatic management of Darier's disease. Dermatol Surg. 2007 Jul. 33(7):882-3. [QxMD MEDLINE Link].
Letulé V, Herzinger T, Ruzicka T, Molin S. Treatment of Darier disease with oral alitretinoin. Clin Exp Dermatol. 2013 Jul. 38(5):523-5. [QxMD MEDLINE Link].
Zamiri M, Munro CS. Successful treatment with oral alitretinoin in women of childbearing potential with Darier's disease. Br J Dermatol. 2013 Sep. 169(3):709-10. [QxMD MEDLINE Link].
Farb RM, Lazarus GS, Chiaramonti A, Goldsmith LA, Gilgor RS, Balakrishnan CV. The effect of 13-cis retinoic acid on epidermal lysosomal hydrolase activity in Darier's disease and pityriasis rubra pilaris. J Invest Dermatol. 1980 Aug. 75(2):133-5. [QxMD MEDLINE Link].
Veit JGS, De Glas V, Balau B, Liu H, Bourlond F, Paller AS, et al. Characterization of CYP26B1-Selective Inhibitor, DX314, as a Potential Therapeutic for Keratinization Disorders. J Invest Dermatol. 2020 Jun 4. [QxMD MEDLINE Link].
Liang J, Chen P, Chen H, Tian X, Wu Z, Zhang S, et al. Long-term safety and efficacy of continuous acitretin monotherapy for three children with different severe hyperkeratotic disorders in China. J Dermatol. 2018 May 14. [QxMD MEDLINE Link].
Suzuki K, Aoki M, Kawana S. Localized Darier's disease of the scalp: successful treatment with oral etretinate. Dermatology. 2004. 208(1):83-4. [QxMD MEDLINE Link].
Kamijo M, Nishiyama C, Takagi A, Nakano N, Hara M, Ikeda S, et al. Cyclooxygenase-2 inhibition restores ultraviolet B-induced downregulation of ATP2A2/SERCA2 in keratinocytes: possible therapeutic approach of cyclooxygenase-2 inhibition for treatment of Darier disease. Br J Dermatol. 2012 May. 166(5):1017-22. [QxMD MEDLINE Link].
Wheeland RG, Gilmore WA. The surgical treatment of hypertrophic Darier's disease. J Dermatol Surg Oncol. 1985 Apr. 11(4):420-3. [QxMD MEDLINE Link].
Toombs EL, Peck GL. Electrosurgical treatment of etretinate-resistant Darier's disease. J Dermatol Surg Oncol. 1989 Dec. 15(12):1277-80. [QxMD MEDLINE Link].
Brown VL, Kelly SE, Burge SM, Walker NP. Extensive recalcitrant Darier disease successfully treated with laser ablation. Br J Dermatol. 2010 Jan. 162(1):227-9. [QxMD MEDLINE Link].
McElroy JA, Mehregan DA, Roenigk RK. Carbon dioxide laser vaporization of recalcitrant symptomatic plaques of Hailey-Hailey disease and Darier's disease. J Am Acad Dermatol. 1990 Nov. 23(5 Pt 1):893-7. [QxMD MEDLINE Link].
Minsue Chen T, Wanitphakdeedecha R, Nguyen TH. Carbon dioxide laser ablation and adjunctive destruction for Darier-White disease (keratosis follicularis). Dermatol Surg. 2008 Oct. 34(10):1431-4. [QxMD MEDLINE Link].
Beier C, Kaufmann R. Efficacy of erbium:YAG laser ablation in Darier disease and Hailey-Hailey disease. Arch Dermatol. 1999 Apr. 135(4):423-7. [QxMD MEDLINE Link].
Roos S, Karsai S, Ockenfel HM, Raulin C. Successful treatment of Darier disease with the flashlamp-pumped pulsed-dye laser. Arch Dermatol. 2008 Aug. 144(8):1073-5. [QxMD MEDLINE Link].
Katz TM, Firoz BF, Goldberg LH, Friedman PM. Treatment of Darier's disease using a 1,550-nm erbium-doped fiber laser. Dermatol Surg. 2010. 36(1):142-6. [QxMD MEDLINE Link].
Krakowski AC, Nguyen TA, Eichenfield LF. Treatment of segmental keratosis follicularis (Darier disease) using ablative fractional laser resurfacing. Dermatol Surg. 2015 Apr. 41 (4):516-8. [QxMD MEDLINE Link].
Minsue Chen T, Wanitphakdeedecha R, Nguyen TH. Carbon dioxide laser ablation and adjunctive destruction for Darier-White disease (keratosis follicularis). Dermatol Surg. 2008 Oct. 34(10):1431-4. [QxMD MEDLINE Link].
Dunnigan AV, Salence B, McPherson T, Walker NPJ. A case of severe refractory Darier's disease of the feet in which management with carbon dioxide (CO2) laser therapy demonstrated superior outcomes to surgical excision. J Cosmet Laser Ther. 2020 Jul 13. 1-3. [QxMD MEDLINE Link].
Kittridge A, Wahlgren C, Fuhrer R, Zirwas M, Patton T. Treatment of recalcitrant Darier's disease with electron beam therapy. Dermatol Ther. 2010 May-Jun. 23(3):302-4. [QxMD MEDLINE Link].
Exadaktylou D, Kurwa HA, Calonje E, Barlow RJ. Treatment of Darier's disease with photodynamic therapy. Br J Dermatol. 2003 Sep. 149(3):606-10. [QxMD MEDLINE Link].
Avery HL, Hughes BR, Coley C, Cooper HL. Clinical improvement in Darier's disease with photodynamic therapy. Australas J Dermatol. 2010 Feb. 51(1):32-5. [QxMD MEDLINE Link].
Ahcan U, Dolenc-Voljc M, Zivec K, Zorman P, Jurcic V. The surgical treatment of hypertrophic intertriginous Darier's disease. J Plast Reconstr Aesthet Surg. 2009 Nov. 62(11):e442-6. [QxMD MEDLINE Link].