Excerpt from Fibrous Papule of the Face

Synonyms, Key Words, and Related Terms: nevus, nevi, nodule, benign skin tumour, reactive nodular hyperplasia, giant cell fibroma

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Background

Fibrous papule of the face is a benign, clinically indistinct papule, which has a characteristic histological appearance.

Pathophysiology

Although Helwig originally suggested that fibrous papule was derived from preexisting or involuting melanocytic nevi, immunostaining has refuted this and has confirmed a relationship to factor XIIIa–positive dermal dendrocytes. They are best considered a variant of solitary angiofibroma.

Frequency

International

The condition is relatively common.

Mortality/Morbidity

Fibrous papule of the face is a benign lesion. Most of the lesions are asymptomatic, although one third of patients have reported bleeding following minor trauma.

Race

No racial predilection is known.

Sex

Both sexes are equally affected.

Age

Most of the patients are in their third to fifth decade of life.

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