Excerpt from Dilated Pore of Winer

Synonyms, Key Words, and Related Terms: Winer's pore, Winer's dilated pore, dilated pore, giant follicle, enlarged solitary comedo, intraepidermal follicle, pilosebaceous apparatus

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Background

A dilated pore of Winer is a hair structure anomaly that appears as an enlarged solitary comedo. Most commonly, it appears on the face of a middle-aged person. This condition is not associated with acne vulgaris.

Pathophysiology

A dilated pore of Winer is a tumor of the intraepidermal follicle and infundibulum of a pilosebaceous apparatus. An immunohistochemical study using monoclonal antibodies against cytokeratins and involucrin confirmed differentiation toward the infundibulum and partly toward the isthmus.

Frequency

United States

Most cases are reported in older adults in both the American and European literature.

Mortality/Morbidity

Death is not associated with a dilated pore of Winer. One case of trichoid basal cell carcinoma in a dilated pore has been reported. More commonly, chronic manipulation and expression of the keratotic plug from inside the pore may lead to inflammation and infection of the surrounding tissue.

Race

Most cases have been reported in white males.

Sex

Although dilated pores are found in both sexes, they appear to occur in men more often than in women.

Age

Most cases are diagnosed in individuals older than 40 years; however, many individuals report that they have had the lesions for many decades, usually starting when they are aged 20-60 years.

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