Excerpt from Dermatosis Papulosa Nigra

Synonyms, Key Words, and Related Terms: DPN, hyperpigmented papules, facial papules, seborrheic keratosis

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Background

Dermatosis papulosa nigra (DPN) is a benign cutaneous condition common among blacks. It is usually characterized by multiple, small, hyperpigmented, asymptomatic papules on the face of adult blacks. Histologically, DPN resembles seborrheic keratoses. The condition may be cosmetically undesirable to some patients.

Pathophysiology

The pathophysiology of DPN is not known. The occasional positive family history may suggest a genetic propensity.

Frequency

United States

Whereas earlier studies revealed a 10% frequency in adult blacks, more recent data suggest a frequency of approximately 35% in this population.

International

Data pertaining to the international frequency of DPN are insufficient.

Mortality/Morbidity

DPN is not associated with any mortality or morbidity.

Race

DPN affects up to 35% of the African American population. Blacks with a fair complexion have the lowest frequency of involvement. DPN also occurs among Asians, although the exact incidence is unknown.

Sex

Females are affected more frequently than males.

Age

DPN usually begins in adolescence and is rare under the age of 7 years. The incidence of DPN, as well as the number and size of individual lesions, increases with age.

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